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Tribromoethyl alcohol  (Synonyms: 2,2,2-Tribromoethanol; Narcolan)

Cat. No.: HY-B1372 Purity: 99.89%
COA Handling Instructions

Molarity Calculator

Tribromoethyl alcohol (2,2,2-Tribromoethanol) is used to animals, particularly rodents, before surgery.

For research use only. We do not sell to patients.

Tribromoethyl alcohol Chemical Structure

Tribromoethyl alcohol Chemical Structure

CAS No. : 75-80-9

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 33 In-stock
Solution
10 mM * 1 mL in DMSO USD 33 In-stock
Solid
500 mg USD 30 In-stock
1 g USD 45 In-stock
5 g   Get quote  
10 g   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 7 publication(s) in Google Scholar

Tribromoethyl alcohol Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

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Description

Tribromoethyl alcohol (2,2,2-Tribromoethanol) is used to animals, particularly rodents, before surgery.

In Vivo

Tribromoethyl alcohol is used to anesthetize laboratory animals, particularly rodents, before surgery.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

282.76

Formula

C2H3Br3O
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

BrC(Br)(Br)CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 125 mg/mL (442.07 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Ethanol : ≥ 100 mg/mL (353.66 mM)

H2O : ≥ 25 mg/mL (88.41 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5366 mL 17.6828 mL 35.3657 mL
5 mM 0.7073 mL 3.5366 mL 7.0731 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  5% Ethanol    95% Saline

    Solubility: 40 mg/mL (141.46 mM); Clear solution; Need ultrasonic

  • Protocol 2

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.08 mg/mL (7.36 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.89%

COA (247 KB) RP-HPLC (114 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / Ethanol / DMSO 1 mM 3.5366 mL 17.6828 mL 35.3657 mL 88.4142 mL
5 mM 0.7073 mL 3.5366 mL 7.0731 mL 17.6828 mL
10 mM 0.3537 mL 1.7683 mL 3.5366 mL 8.8414 mL
15 mM 0.2358 mL 1.1789 mL 2.3577 mL 5.8943 mL
20 mM 0.1768 mL 0.8841 mL 1.7683 mL 4.4207 mL
25 mM 0.1415 mL 0.7073 mL 1.4146 mL 3.5366 mL
30 mM 0.1179 mL 0.5894 mL 1.1789 mL 2.9471 mL
40 mM 0.0884 mL 0.4421 mL 0.8841 mL 2.2104 mL
50 mM 0.0707 mL 0.3537 mL 0.7073 mL 1.7683 mL
60 mM 0.0589 mL 0.2947 mL 0.5894 mL 1.4736 mL
80 mM 0.0442 mL 0.2210 mL 0.4421 mL 1.1052 mL
Ethanol / DMSO 100 mM 0.0354 mL 0.1768 mL 0.3537 mL 0.8841 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Tribromoethyl alcohol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tribromoethyl alcohol75-80-92,2,2-Tribromoethanol NarcolanOthersInhibitorinhibitorinhibit

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