2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 2',3'-O-Isopropylideneadenosine

2',3'-O-Isopropylideneadenosine 

Cat. No.: HY-W008048 Purity: ≥98.0%
COA Handling Instructions

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2',3'-O-Isopropylideneadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).

For research use only. We do not sell to patients.

2',3'-O-Isopropylideneadenosine Chemical Structure

2',3'-O-Isopropylideneadenosine Chemical Structure

CAS No. : 362-75-4

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5 g USD 40 Ask For Quote & Lead Time

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2',3'-O-Isopropylideneadenosine Related Antibodies

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Description

2',3'-O-Isopropylideneadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

Molecular Weight

307.31

Formula

C13H17N5O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NC1=NC=NC2=C1N=CN2[C@H]3[C@H]4[C@H](OC(C)(C)O4)[C@@H](CO)O3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (325.40 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2540 mL 16.2702 mL 32.5404 mL
5 mM 0.6508 mL 3.2540 mL 6.5081 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.97%

COA (255 KB) HNMR (132 KB) RP-HPLC (224 KB) MS (105 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2540 mL 16.2702 mL 32.5404 mL 81.3511 mL
5 mM 0.6508 mL 3.2540 mL 6.5081 mL 16.2702 mL
10 mM 0.3254 mL 1.6270 mL 3.2540 mL 8.1351 mL
15 mM 0.2169 mL 1.0847 mL 2.1694 mL 5.4234 mL
20 mM 0.1627 mL 0.8135 mL 1.6270 mL 4.0676 mL
25 mM 0.1302 mL 0.6508 mL 1.3016 mL 3.2540 mL
30 mM 0.1085 mL 0.5423 mL 1.0847 mL 2.7117 mL
40 mM 0.0814 mL 0.4068 mL 0.8135 mL 2.0338 mL
50 mM 0.0651 mL 0.3254 mL 0.6508 mL 1.6270 mL
60 mM 0.0542 mL 0.2712 mL 0.5423 mL 1.3559 mL
80 mM 0.0407 mL 0.2034 mL 0.4068 mL 1.0169 mL
100 mM 0.0325 mL 0.1627 mL 0.3254 mL 0.8135 mL
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2',3'-O-Isopropylideneadenosine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2',3'-O-Isopropylideneadenosine362-75-4Nucleoside Antimetabolite/Analogmuscle vasodilatorInhibitorinhibitorinhibit

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