1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. 2,4-D-d3

2,4-D-d3 is the deuterium labeled 2,4-D[1]. 2,4-D (2,4-Dichlorophenoxyacetic acid) is a selective systemic herbicide for the control of broad-leaved weeds. 2,4-D acts as a plant hormone, causing uncontrolled growth in the meristematic tissues. 2,4-D inhibits DNA and protein synthesis and thereby prevents normal plant growth and development[2].

For research use only. We do not sell to patients.

2,4-D-d<sub>3</sub> Chemical Structure

2,4-D-d3 Chemical Structure

CAS No. : 202480-67-9

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Description

2,4-D-d3 is the deuterium labeled 2,4-D[1]. 2,4-D (2,4-Dichlorophenoxyacetic acid) is a selective systemic herbicide for the control of broad-leaved weeds. 2,4-D acts as a plant hormone, causing uncontrolled growth in the meristematic tissues. 2,4-D inhibits DNA and protein synthesis and thereby prevents normal plant growth and development[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

224.06

Formula

C8H3D3Cl2O3

CAS No.
Unlabeled CAS

94-75-7

SMILES

OC(COC1=C(C([2H])=C(C([2H])=C1[2H])Cl)Cl)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (446.31 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4631 mL 22.3155 mL 44.6309 mL
5 mM 0.8926 mL 4.4631 mL 8.9262 mL
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Purity & Documentation
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Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.4631 mL 22.3155 mL 44.6309 mL 111.5773 mL
5 mM 0.8926 mL 4.4631 mL 8.9262 mL 22.3155 mL
10 mM 0.4463 mL 2.2315 mL 4.4631 mL 11.1577 mL
15 mM 0.2975 mL 1.4877 mL 2.9754 mL 7.4385 mL
20 mM 0.2232 mL 1.1158 mL 2.2315 mL 5.5789 mL
25 mM 0.1785 mL 0.8926 mL 1.7852 mL 4.4631 mL
30 mM 0.1488 mL 0.7438 mL 1.4877 mL 3.7192 mL
40 mM 0.1116 mL 0.5579 mL 1.1158 mL 2.7894 mL
50 mM 0.0893 mL 0.4463 mL 0.8926 mL 2.2315 mL
60 mM 0.0744 mL 0.3719 mL 0.7438 mL 1.8596 mL
80 mM 0.0558 mL 0.2789 mL 0.5579 mL 1.3947 mL
100 mM 0.0446 mL 0.2232 mL 0.4463 mL 1.1158 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
2,4-D-d3
Cat. No.:
HY-18572S1
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