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  4. 2,6-Dichloro-4-iodopyridine

2,6-Dichloro-4-iodopyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

2,6-Dichloro-4-iodopyridine Chemical Structure

2,6-Dichloro-4-iodopyridine Chemical Structure

CAS No. : 98027-84-0

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Based on 1 publication(s) in Google Scholar

2,6-Dichloro-4-iodopyridine Related Antibodies

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  • Purity & Documentation

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Description

2,6-Dichloro-4-iodopyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Molecular Weight

273.89

Formula

C5H2Cl2IN
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

ClC1=CC(I)=CC(Cl)=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

DMSO : 33.33 mg/mL (121.69 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6511 mL 18.2555 mL 36.5110 mL
5 mM 0.7302 mL 3.6511 mL 7.3022 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 2.5 mg/mL (9.13 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).

*The compound is unstable in solutions, freshly prepared is recommended.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation

Purity: 99.62%

COA (249 KB) HNMR (232 KB) LCMS (95 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6511 mL 18.2555 mL 36.5110 mL 91.2775 mL
5 mM 0.7302 mL 3.6511 mL 7.3022 mL 18.2555 mL
10 mM 0.3651 mL 1.8256 mL 3.6511 mL 9.1278 mL
15 mM 0.2434 mL 1.2170 mL 2.4341 mL 6.0852 mL
20 mM 0.1826 mL 0.9128 mL 1.8256 mL 4.5639 mL
25 mM 0.1460 mL 0.7302 mL 1.4604 mL 3.6511 mL
30 mM 0.1217 mL 0.6085 mL 1.2170 mL 3.0426 mL
40 mM 0.0913 mL 0.4564 mL 0.9128 mL 2.2819 mL
50 mM 0.0730 mL 0.3651 mL 0.7302 mL 1.8256 mL
60 mM 0.0609 mL 0.3043 mL 0.6085 mL 1.5213 mL
80 mM 0.0456 mL 0.2282 mL 0.4564 mL 1.1410 mL
100 mM 0.0365 mL 0.1826 mL 0.3651 mL 0.9128 mL
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2,6-Dichloro-4-iodopyridine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2,6-Dichloro-4-iodopyridine98027-84-0Biochemical Assay Reagentsbiochemical reagentbiological materialorganic compoundlife scienceInhibitorinhibitorinhibit

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