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  3. 2-Methoxyphenothiazine

2-Methoxyphenothiazine  (Synonyms: 2-Methoxy-10H-phenothiazine)

Cat. No.: HY-W012258 Purity: 99.61%
Handling Instructions Technical Support

2-Methoxyphenothiazine (2-Methoxy-10H-phenothiazine) is an active compound. 2-Methoxyphenothiazine can be used for the research of various biochemical studies.

For research use only. We do not sell to patients.

2-Methoxyphenothiazine Chemical Structure

2-Methoxyphenothiazine Chemical Structure

CAS No. : 1771-18-2

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
10 mM * 1 mL in DMSO In-stock
Solid
25 g In-stock
50 g In-stock
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Description

2-Methoxyphenothiazine (2-Methoxy-10H-phenothiazine) is an active compound. 2-Methoxyphenothiazine can be used for the research of various biochemical studies[1].

Cellular Effect
Cell Line Type Value Description References
HT-1080 EC50
1.748 μM
Compound: P23
Inhibition of erastin-induced ferroptosis in human HT-1080 cells assessed as cell viability incubated for 48 hrs by MTT assay
Inhibition of erastin-induced ferroptosis in human HT-1080 cells assessed as cell viability incubated for 48 hrs by MTT assay
[PMID: 33065375]
Molecular Weight

229.30

Formula

C13H11NOS

CAS No.
Appearance

Solid

Color

Off-white to gray

SMILES

COC1=CC(NC2=CC=CC=C2S3)=C3C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (436.10 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.3610 mL 21.8051 mL 43.6102 mL
5 mM 0.8722 mL 4.3610 mL 8.7220 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.61%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.3610 mL 21.8051 mL 43.6102 mL 109.0256 mL
5 mM 0.8722 mL 4.3610 mL 8.7220 mL 21.8051 mL
10 mM 0.4361 mL 2.1805 mL 4.3610 mL 10.9026 mL
15 mM 0.2907 mL 1.4537 mL 2.9073 mL 7.2684 mL
20 mM 0.2181 mL 1.0903 mL 2.1805 mL 5.4513 mL
25 mM 0.1744 mL 0.8722 mL 1.7444 mL 4.3610 mL
30 mM 0.1454 mL 0.7268 mL 1.4537 mL 3.6342 mL
40 mM 0.1090 mL 0.5451 mL 1.0903 mL 2.7256 mL
50 mM 0.0872 mL 0.4361 mL 0.8722 mL 2.1805 mL
60 mM 0.0727 mL 0.3634 mL 0.7268 mL 1.8171 mL
80 mM 0.0545 mL 0.2726 mL 0.5451 mL 1.3628 mL
100 mM 0.0436 mL 0.2181 mL 0.4361 mL 1.0903 mL
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2-Methoxyphenothiazine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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