2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 2-Thiocytidine

2-Thiocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

2-Thiocytidine Chemical Structure

2-Thiocytidine Chemical Structure

CAS No. : 13239-97-9

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5 mg USD 57 In-stock
10 mg USD 98 In-stock
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Based on 1 publication(s) in Google Scholar

2-Thiocytidine Related Antibodies

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Description

2-Thiocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Molecular Weight

259.28

Formula

C9H13N3O4S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

S=C1N([C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2)C=CC(N)=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (482.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8568 mL 19.2842 mL 38.5683 mL
5 mM 0.7714 mL 3.8568 mL 7.7137 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.8568 mL 19.2842 mL 38.5683 mL 96.4209 mL
5 mM 0.7714 mL 3.8568 mL 7.7137 mL 19.2842 mL
10 mM 0.3857 mL 1.9284 mL 3.8568 mL 9.6421 mL
15 mM 0.2571 mL 1.2856 mL 2.5712 mL 6.4281 mL
20 mM 0.1928 mL 0.9642 mL 1.9284 mL 4.8210 mL
25 mM 0.1543 mL 0.7714 mL 1.5427 mL 3.8568 mL
30 mM 0.1286 mL 0.6428 mL 1.2856 mL 3.2140 mL
40 mM 0.0964 mL 0.4821 mL 0.9642 mL 2.4105 mL
50 mM 0.0771 mL 0.3857 mL 0.7714 mL 1.9284 mL
60 mM 0.0643 mL 0.3214 mL 0.6428 mL 1.6070 mL
80 mM 0.0482 mL 0.2411 mL 0.4821 mL 1.2053 mL
100 mM 0.0386 mL 0.1928 mL 0.3857 mL 0.9642 mL
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2-Thiocytidine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Thiocytidine13239-97-9Nucleoside Antimetabolite/Analogindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

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