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  6. (25R)-Spirost-4-ene-3,12-dione

(25R)-Spirost-4-ene-3,12-dione  (Synonyms: (-)-(25R)-Spirost-4-ene-3,12-dione)

Cat. No.: HY-N7885 Purity: 99.61%
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(25R)-Spirost-4-ene-3,12-dione ((-)-(25R)-Spirost-4-ene-3,12-dione) is a natural product that has an inhibitory effect on neutrophil superoxide anion production and histamine release from mast cells.

For research use only. We do not sell to patients.

(25R)-Spirost-4-ene-3,12-dione Chemical Structure

(25R)-Spirost-4-ene-3,12-dione Chemical Structure

CAS No. : 6875-60-1

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Description

(25R)-Spirost-4-ene-3,12-dione ((-)-(25R)-Spirost-4-ene-3,12-dione) is a natural product that has an inhibitory effect on neutrophil superoxide anion production and histamine release from mast cells[1].

Molecular Weight

426.59

Formula

C27H38O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[H][C@]1(O[C@@]2(OC[C@H](C)CC2)[C@@H](C)[C@@]1([C@]34C)[H])C[C@@]3([H])[C@]5([H])CCC6=CC(CC[C@]6(C)[C@@]5([H])CC4=O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 3.33 mg/mL (7.81 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3442 mL 11.7209 mL 23.4417 mL
5 mM 0.4688 mL 2.3442 mL 4.6883 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3442 mL 11.7209 mL 23.4417 mL 58.6043 mL
5 mM 0.4688 mL 2.3442 mL 4.6883 mL 11.7209 mL
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(25R)-Spirost-4-ene-3,12-dione Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(25R)-Spirost-4-ene-3,12-dione6875-60-1(-)-(25R)-Spirost-4-ene-3,12-dioneOthersnatural productneutrophilmast cellshistamineInhibitorinhibitorinhibit

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