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  4. 3,3'-Diethyloxacarbocyanine iodide

3,3'-Diethyloxacarbocyanine iodide 

Cat. No.: HY-W040258 Purity: 99.79%
SDS COA Handling Instructions

Molarity Calculator

3,3'-Diethyloxacarbocyanine iodide is a microviscosity probe for micelles and microemulsions.

For research use only. We do not sell to patients.

3,3'-Diethyloxacarbocyanine iodide Chemical Structure

3,3'-Diethyloxacarbocyanine iodide Chemical Structure

CAS No. : 905-96-4

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Based on 1 publication(s) in Google Scholar

3,3'-Diethyloxacarbocyanine iodide Related Antibodies

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Description

3,3'-Diethyloxacarbocyanine iodide is a microviscosity probe for micelles and microemulsions[1].

Molecular Weight

460.31

Formula

C21H21IN2O2
CAS No.
Appearance

Solid

Color

Purple to purplish red

SMILES

CCN1C2=C(C=CC=C2)O/C1=C/C=C/C(OC3=C4C=CC=C3)=[N+]4CC.[I-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 20.83 mg/mL (45.25 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1724 mL 10.8622 mL 21.7245 mL
5 mM 0.4345 mL 2.1724 mL 4.3449 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.08 mg/mL (4.52 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation

Purity: 99.79%

SDS (252 KB)

COA (252 KB) HNMR (260 KB) LCMS (267 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1724 mL 10.8622 mL 21.7245 mL 54.3112 mL
5 mM 0.4345 mL 2.1724 mL 4.3449 mL 10.8622 mL
10 mM 0.2172 mL 1.0862 mL 2.1724 mL 5.4311 mL
15 mM 0.1448 mL 0.7241 mL 1.4483 mL 3.6207 mL
20 mM 0.1086 mL 0.5431 mL 1.0862 mL 2.7156 mL
25 mM 0.0869 mL 0.4345 mL 0.8690 mL 2.1724 mL
30 mM 0.0724 mL 0.3621 mL 0.7241 mL 1.8104 mL
40 mM 0.0543 mL 0.2716 mL 0.5431 mL 1.3578 mL
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3,3'-Diethyloxacarbocyanine iodide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3,3'-Diethyloxacarbocyanine905-96-4Biochemical Assay ReagentsInhibitorinhibitorinhibit

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