3,4-Dichloroisocoumarin

Cat. No.: HY-126034 Purity: 99.72%: FAQs
Data Sheet SDS COA Handling Instructions

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3,4-Dichloroisocoumarin is a potent serine-protease inhibitor that inhibits chymotrypsin-like activity.

For research use only. We do not sell to patients.

3,4-Dichloroisocoumarin Chemical Structure

CAS No. : 51050-59-0

Size	Price	Stock	Quantity
1 mg	USD 37	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 110	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 190	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

3,4-Dichloroisocoumarin is a potent serine-protease inhibitor that inhibits chymotrypsin-like activity^[1].

Molecular Weight

215.03

Formula

C₉H₄Cl₂O₂

CAS No.

51050-59-0

Appearance

Solid

Color

White to off-white

SMILES

ClC1=C(OC(C2=C1C=CC=C2)=O)Cl

Structure Classification

Initial Source

Animals

pig

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (465.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.6505 mL	23.2526 mL	46.5051 mL
5 mM	0.9301 mL	4.6505 mL	9.3010 mL
10 mM	0.4651 mL	2.3253 mL	4.6505 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.72%

Select Batch:

Data Sheet (272 KB) SDS (480 KB)

COA (254 KB) HNMR (244 KB) LCMS (93 KB)

Handling Instructions (2659 KB)

References

[1]. H Djaballah, et al. Use of serine-protease inhibitors as probes for the different proteolytic activities of the rat liver multicatalytic proteinase complex. Eur J Biochem. 1992 Oct 15;209(2):629-34. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.6505 mL	23.2526 mL	46.5051 mL	116.2628 mL
	5 mM	0.9301 mL	4.6505 mL	9.3010 mL	23.2526 mL
	10 mM	0.4651 mL	2.3253 mL	4.6505 mL	11.6263 mL
	15 mM	0.3100 mL	1.5502 mL	3.1003 mL	7.7509 mL
	20 mM	0.2325 mL	1.1626 mL	2.3253 mL	5.8131 mL
	25 mM	0.1860 mL	0.9301 mL	1.8602 mL	4.6505 mL
	30 mM	0.1550 mL	0.7751 mL	1.5502 mL	3.8754 mL
	40 mM	0.1163 mL	0.5813 mL	1.1626 mL	2.9066 mL
	50 mM	0.0930 mL	0.4651 mL	0.9301 mL	2.3253 mL
	60 mM	0.0775 mL	0.3875 mL	0.7751 mL	1.9377 mL
	80 mM	0.0581 mL	0.2907 mL	0.5813 mL	1.4533 mL
	100 mM	0.0465 mL	0.2325 mL	0.4651 mL	1.1626 mL