1. Metabolic Enzyme/Protease
  2. Ser/Thr Protease
  3. 3,4-Dichloroisocoumarin

3,4-Dichloroisocoumarin is a potent serine-protease inhibitor that inhibits chymotrypsin-like activity.

For research use only. We do not sell to patients.

3,4-Dichloroisocoumarin Chemical Structure

3,4-Dichloroisocoumarin Chemical Structure

CAS No. : 51050-59-0

Size Price Stock Quantity
1 mg USD 37 In-stock
5 mg USD 110 In-stock
10 mg USD 190 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

3,4-Dichloroisocoumarin is a potent serine-protease inhibitor that inhibits chymotrypsin-like activity[1].

Molecular Weight

215.03

Formula

C9H4Cl2O2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

ClC1=C(OC(C2=C1C=CC=C2)=O)Cl

Structure Classification
Initial Source

pig

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (465.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.6505 mL 23.2526 mL 46.5051 mL
5 mM 0.9301 mL 4.6505 mL 9.3010 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.72%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.6505 mL 23.2526 mL 46.5051 mL 116.2628 mL
5 mM 0.9301 mL 4.6505 mL 9.3010 mL 23.2526 mL
10 mM 0.4651 mL 2.3253 mL 4.6505 mL 11.6263 mL
15 mM 0.3100 mL 1.5502 mL 3.1003 mL 7.7509 mL
20 mM 0.2325 mL 1.1626 mL 2.3253 mL 5.8131 mL
25 mM 0.1860 mL 0.9301 mL 1.8602 mL 4.6505 mL
30 mM 0.1550 mL 0.7751 mL 1.5502 mL 3.8754 mL
40 mM 0.1163 mL 0.5813 mL 1.1626 mL 2.9066 mL
50 mM 0.0930 mL 0.4651 mL 0.9301 mL 2.3253 mL
60 mM 0.0775 mL 0.3875 mL 0.7751 mL 1.9377 mL
80 mM 0.0581 mL 0.2907 mL 0.5813 mL 1.4533 mL
100 mM 0.0465 mL 0.2325 mL 0.4651 mL 1.1626 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
3,4-Dichloroisocoumarin
Cat. No.:
HY-126034
Quantity:
MCE Japan Authorized Agent: