2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 4,10-Dioxatri cyclo[5.2. 1.02.6]dec-8-ene-3,5-dione

4,10-Dioxatri cyclo[5.2. 1.02.6]dec-8-ene-3,5-dione  (Synonyms: 7-Oxanorborna-2-ene-5,6-dicarboxylic anhydride)

Cat. No.: HY-W102981 Purity: ≥97.0%
SDS COA Handling Instructions

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4,10-Dioxatri cyclo[5.2. 1.02.6]dec-8-ene-3,5-dione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

4,10-Dioxatri cyclo[5.2. 1.02.6]dec-8-ene-3,5-dione Chemical Structure

4,10-Dioxatri cyclo[5.2. 1.02.6]dec-8-ene-3,5-dione Chemical Structure

CAS No. : 5426-09-5

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 33 In-stock
Solution
10 mM * 1 mL in DMSO USD 33 In-stock
Solid
1 g USD 30 Get quote
5 g USD 70 Get quote
10 g   Get quote  
50 g   Get quote  

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Based on 1 publication(s) in Google Scholar

4,10-Dioxatri cyclo[5.2. 1.02.6]dec-8-ene-3,5-dione Related Antibodies

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Description

4,10-Dioxatri cyclo[5.2. 1.02.6]dec-8-ene-3,5-dione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Molecular Weight

166.13

Formula

C8H6O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C1=CC2C3C(C1O2)C(=O)OC3=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (601.94 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.0194 mL 30.0969 mL 60.1938 mL
5 mM 1.2039 mL 6.0194 mL 12.0388 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥97.0%

SDS (393 KB)

COA (261 KB) HNMR (127 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.0194 mL 30.0969 mL 60.1938 mL 150.4846 mL
5 mM 1.2039 mL 6.0194 mL 12.0388 mL 30.0969 mL
10 mM 0.6019 mL 3.0097 mL 6.0194 mL 15.0485 mL
15 mM 0.4013 mL 2.0065 mL 4.0129 mL 10.0323 mL
20 mM 0.3010 mL 1.5048 mL 3.0097 mL 7.5242 mL
25 mM 0.2408 mL 1.2039 mL 2.4078 mL 6.0194 mL
30 mM 0.2006 mL 1.0032 mL 2.0065 mL 5.0162 mL
40 mM 0.1505 mL 0.7524 mL 1.5048 mL 3.7621 mL
50 mM 0.1204 mL 0.6019 mL 1.2039 mL 3.0097 mL
60 mM 0.1003 mL 0.5016 mL 1.0032 mL 2.5081 mL
80 mM 0.0752 mL 0.3762 mL 0.7524 mL 1.8811 mL
100 mM 0.0602 mL 0.3010 mL 0.6019 mL 1.5048 mL
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4,10-Dioxatri cyclo[5.2. 1.02.6]dec-8-ene-3,5-dione Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4,10-Dioxatri cyclo[5.2. 1.02.6]dec-8-ene-3,5-dione5426-09-57-Oxanorborna-2-ene-5,6-dicarboxylic anhydrideNucleoside Antimetabolite/Analogindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

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