4-(4-chlorophenyl)thiazol-2-amine

Cat. No.: HY-W052190 Purity: 99.84%: FAQs
Data Sheet SDS COA Handling Instructions

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4-(4-chlorophenyl)thiazol-2-amine (Compound A) is the derivative of Aminothiazole (HY-12396).

For research use only. We do not sell to patients.

4-(4-chlorophenyl)thiazol-2-amine Chemical Structure

CAS No. : 2103-99-3

Size	Stock	Quantity

Free Sample (0.1 - 0.5 mg)	Apply Now
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	Get quote	Estimated Time of Arrival: December 31
10 g	Get quote
50 g	Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

4-(4-chlorophenyl)thiazol-2-amine (Compound A) is the derivative of Aminothiazole (HY-12396)^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HUVEC	IC₅₀	> 10 μM Compound: 22	Antiangiogenic activity against human HUVEC cells assessed as inhibition of [3H]thymidine incorporation incubated for 24 hrs prior to [3H]thymidine addition measured after 6 hrs by microbeta counting analysis Antiangiogenic activity against human HUVEC cells assessed as inhibition of [3H]thymidine incorporation incubated for 24 hrs prior to [3H]thymidine addition measured after 6 hrs by microbeta counting analysis	[PMID: 23518276]

Molecular Weight

210.69

Formula

C₉H₇ClN₂S

CAS No.

2103-99-3

Appearance

Solid

SMILES

ClC1=CC=C(C2=CSC(N)=N2)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : ≥ 200 mg/mL (949.27 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.7463 mL	23.7317 mL	47.4633 mL
5 mM	0.9493 mL	4.7463 mL	9.4927 mL
10 mM	0.4746 mL	2.3732 mL	4.7463 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.84%

Select Batch:

Data Sheet (268 KB) SDS (420 KB)

COA (247 KB) HNMR (114 KB) RP-HPLC (185 KB)

Handling Instructions (2659 KB)

References

[1]. Caba-Flores MD, et al., Activity In Vitro of 2-Chloro-N-[4-(4-Chlorophenyl)-2-Thiazolyl]Acetamide Against Promastigotes of Leishmania mexicana: An Apoptosis Inducer. Acta Parasitol. 2021 Sep;66(3):1068-1073. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.7463 mL	23.7317 mL	47.4633 mL	118.6583 mL
	5 mM	0.9493 mL	4.7463 mL	9.4927 mL	23.7317 mL
	10 mM	0.4746 mL	2.3732 mL	4.7463 mL	11.8658 mL
	15 mM	0.3164 mL	1.5821 mL	3.1642 mL	7.9106 mL
	20 mM	0.2373 mL	1.1866 mL	2.3732 mL	5.9329 mL
	25 mM	0.1899 mL	0.9493 mL	1.8985 mL	4.7463 mL
	30 mM	0.1582 mL	0.7911 mL	1.5821 mL	3.9553 mL
	40 mM	0.1187 mL	0.5933 mL	1.1866 mL	2.9665 mL
	50 mM	0.0949 mL	0.4746 mL	0.9493 mL	2.3732 mL
	60 mM	0.0791 mL	0.3955 mL	0.7911 mL	1.9776 mL
	80 mM	0.0593 mL	0.2966 mL	0.5933 mL	1.4832 mL
	100 mM	0.0475 mL	0.2373 mL	0.4746 mL	1.1866 mL