2. Apoptosis
  3. Bcl-2 Family
  4. 4-(4-Fluorophenyl)benzoic acid

4-(4-Fluorophenyl)benzoic acid 

Cat. No.: HY-109617 Purity: 99.01%
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4-(4-Fluorophenyl)benzoic acid (Compoud 6) can bind to Bcl-2 with a KD value of 400 μM. 4-(4-Fluorophenyl)benzoic acid can be used to develope Bcl-2 selective anti-cancer agent.

For research use only. We do not sell to patients.

4-(4-Fluorophenyl)benzoic acid Chemical Structure

4-(4-Fluorophenyl)benzoic acid Chemical Structure

CAS No. : 5731-10-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 27 In-stock
Solution
10 mM * 1 mL in DMSO USD 27 In-stock
Solid
10 mg USD 25 In-stock
25 mg USD 48 In-stock
50 mg USD 70 In-stock
100 mg USD 98 In-stock
200 mg   Get quote  
500 mg   Get quote  

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4-(4-Fluorophenyl)benzoic acid Related Antibodies

Top Publications Citing Use of Products

View All Bcl-2 Family Isoform Specific Products:

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Bcl-2 Bcl-xL Bcl-W Mcl-1 Bfl-1 Bcl-B Bax Bak Bim

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Description

4-(4-Fluorophenyl)benzoic acid (Compoud 6) can bind to Bcl-2 with a KD value of 400 μM. 4-(4-Fluorophenyl)benzoic acid can be used to develope Bcl-2 selective anti-cancer agent[1].

Molecular Weight

216.21

Formula

C13H9FO2
CAS No.
Appearance

Solid

Color

Gray to brown

SMILES

O=C(C1=CC=C(C2=CC=C(F)C=C2)C=C1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 125 mg/mL (578.14 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.6251 mL 23.1257 mL 46.2513 mL
5 mM 0.9250 mL 4.6251 mL 9.2503 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.6251 mL 23.1257 mL 46.2513 mL 115.6283 mL
5 mM 0.9250 mL 4.6251 mL 9.2503 mL 23.1257 mL
10 mM 0.4625 mL 2.3126 mL 4.6251 mL 11.5628 mL
15 mM 0.3083 mL 1.5417 mL 3.0834 mL 7.7086 mL
20 mM 0.2313 mL 1.1563 mL 2.3126 mL 5.7814 mL
25 mM 0.1850 mL 0.9250 mL 1.8501 mL 4.6251 mL
30 mM 0.1542 mL 0.7709 mL 1.5417 mL 3.8543 mL
40 mM 0.1156 mL 0.5781 mL 1.1563 mL 2.8907 mL
50 mM 0.0925 mL 0.4625 mL 0.9250 mL 2.3126 mL
60 mM 0.0771 mL 0.3854 mL 0.7709 mL 1.9271 mL
80 mM 0.0578 mL 0.2891 mL 0.5781 mL 1.4454 mL
100 mM 0.0463 mL 0.2313 mL 0.4625 mL 1.1563 mL
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4-(4-Fluorophenyl)benzoic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-(4-Fluorophenyl)benzoic acid5731-10-2Bcl-2 FamilyInhibitorinhibitorinhibit

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