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  4. 4,7-Dibromo-2,1,3-benzothiadiazole

4,7-Dibromo-2,1,3-benzothiadiazole 

Cat. No.: HY-W002651 Purity: 99.52%
COA Handling Instructions

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4,7-Dibromo-2,1,3-benzothiadiazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

4,7-Dibromo-2,1,3-benzothiadiazole Chemical Structure

4,7-Dibromo-2,1,3-benzothiadiazole Chemical Structure

CAS No. : 15155-41-6

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Based on 1 publication(s) in Google Scholar

4,7-Dibromo-2,1,3-benzothiadiazole Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

4,7-Dibromo-2,1,3-benzothiadiazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Molecular Weight

293.97

Formula

C6H2Br2N2S
CAS No.
Appearance

Solid

Color

Light yellow to brown

SMILES

BrC1=CC=C(Br)C2=NSN=C21
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (85.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4017 mL 17.0085 mL 34.0171 mL
5 mM 0.6803 mL 3.4017 mL 6.8034 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 2.5 mg/mL (8.50 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation

Purity: 99.89%

COA (254 KB) HNMR (117 KB) RP-HPLC (95 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4017 mL 17.0085 mL 34.0171 mL 85.0427 mL
5 mM 0.6803 mL 3.4017 mL 6.8034 mL 17.0085 mL
10 mM 0.3402 mL 1.7009 mL 3.4017 mL 8.5043 mL
15 mM 0.2268 mL 1.1339 mL 2.2678 mL 5.6695 mL
20 mM 0.1701 mL 0.8504 mL 1.7009 mL 4.2521 mL
25 mM 0.1361 mL 0.6803 mL 1.3607 mL 3.4017 mL
30 mM 0.1134 mL 0.5670 mL 1.1339 mL 2.8348 mL
40 mM 0.0850 mL 0.4252 mL 0.8504 mL 2.1261 mL
50 mM 0.0680 mL 0.3402 mL 0.6803 mL 1.7009 mL
60 mM 0.0567 mL 0.2835 mL 0.5670 mL 1.4174 mL
80 mM 0.0425 mL 0.2126 mL 0.4252 mL 1.0630 mL
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4,7-Dibromo-2,1,3-benzothiadiazole Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4,7-Dibromo-2,1,3-benzothiadiazole15155-41-6Biochemical Assay Reagentsbiochemical reagentbiological materialorganic compoundlife scienceInhibitorinhibitorinhibit

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