2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 4-Aminohippuric acid-d4

4-Aminohippuric acid-d4  (Synonyms: p-Aminohippuric acid-d4)

Cat. No.: HY-B1306S Purity: ≥98.0%
SDS COA Handling Instructions

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4-Aminohippuric acid-d4 is the deuterium labeled 4-Aminohippuric acid. 4-Aminohippuric acid is a diagnostic agent, useful in medical tests involving the kidney, used in the measurement of renal plasma flow.

For research use only. We do not sell to patients.

4-Aminohippuric acid-d<sub>4</sub> Chemical Structure

4-Aminohippuric acid-d4 Chemical Structure

CAS No. : 1219805-41-0

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Based on 1 publication(s) in Google Scholar

Other Forms of 4-Aminohippuric acid-d4:

4-Aminohippuric acid-d4 Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

4-Aminohippuric acid-d4 is the deuterium labeled 4-Aminohippuric acid. 4-Aminohippuric acid is a diagnostic agent, useful in medical tests involving the kidney, used in the measurement of renal plasma flow.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

4-Aminohippuric acid-d4 Related Antibodies
Molecular Weight

198.21

Formula

C9H6D4N2O3
CAS No.
Unlabeled CAS

61-78-9
Appearance

Solid

Color

Off-white to light yellow

SMILES

OC(CNC(C1=C([2H])C([2H])=C(C([2H])=C1[2H])N)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMF : ≥ 33 mg/mL (166.49 mM)

DMF : ≥ 33 mg/mL (166.49 mM)

DMSO : ≥ 20 mg/mL (100.90 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 20 mg/mL (100.90 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMF:PBS (pH7.2) (1:30) : ≥ 0.03 mg/mL (0.15 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.0452 mL 25.2258 mL 50.4515 mL
5 mM 1.0090 mL 5.0452 mL 10.0903 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

SDS (251 KB)

COA (247 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO / DMF / DMF 1 mM 5.0452 mL 25.2258 mL 50.4515 mL 126.1288 mL
5 mM 1.0090 mL 5.0452 mL 10.0903 mL 25.2258 mL
10 mM 0.5045 mL 2.5226 mL 5.0452 mL 12.6129 mL
15 mM 0.3363 mL 1.6817 mL 3.3634 mL 8.4086 mL
20 mM 0.2523 mL 1.2613 mL 2.5226 mL 6.3064 mL
25 mM 0.2018 mL 1.0090 mL 2.0181 mL 5.0452 mL
30 mM 0.1682 mL 0.8409 mL 1.6817 mL 4.2043 mL
40 mM 0.1261 mL 0.6306 mL 1.2613 mL 3.1532 mL
50 mM 0.1009 mL 0.5045 mL 1.0090 mL 2.5226 mL
60 mM 0.0841 mL 0.4204 mL 0.8409 mL 2.1021 mL
80 mM 0.0631 mL 0.3153 mL 0.6306 mL 1.5766 mL
100 mM 0.0505 mL 0.2523 mL 0.5045 mL 1.2613 mL
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4-Aminohippuric acid-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-Aminohippuric acid-d41219805-41-0p-Aminohippuric acid-d4Endogenous MetaboliteInhibitorinhibitorinhibit

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