2. Metabolic Enzyme/Protease Others
  3. Endogenous Metabolite Isotope-Labeled Compounds
  4. 4-Hydroxyestrone-d4

4-Hydroxyestrone-d4  (Synonyms: 4-OHE1-d4)

Cat. No.: HY-W009300S Purity: 98.00%
COA Handling Instructions

Molarity Calculator

4-Hydroxyestrone-d4 is the deuterium labeled 4-Hydroxyestrone[1].

For research use only. We do not sell to patients.

4-Hydroxyestrone-d<sub>4</sub> Chemical Structure

4-Hydroxyestrone-d4 Chemical Structure

CAS No. : 81586-98-3

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Based on 1 publication(s) in Google Scholar

Other Forms of 4-Hydroxyestrone-d4:

4-Hydroxyestrone-d4 Related Antibodies

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Description

4-Hydroxyestrone-d4 is the deuterium labeled 4-Hydroxyestrone[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

4-Hydroxyestrone-d4 Related Antibodies
Molecular Weight

290.39

Formula

C18H18D4O3
CAS No.
Unlabeled CAS

3131-23-5
Appearance

Solid

Color

Off-white to gray

SMILES

C[C@@]12[C@](CC([2H])([2H])C2=O)([H])[C@@]3([H])[C@@](CC1)([H])C4=C([2H])C([2H])=C(O)C(O)=C4CC3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

Methanol : 10 mg/mL (34.44 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4436 mL 17.2182 mL 34.4364 mL
5 mM 0.6887 mL 3.4436 mL 6.8873 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.00%

COA (253 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Methanol 1 mM 3.4436 mL 17.2182 mL 34.4364 mL 86.0911 mL
5 mM 0.6887 mL 3.4436 mL 6.8873 mL 17.2182 mL
10 mM 0.3444 mL 1.7218 mL 3.4436 mL 8.6091 mL
15 mM 0.2296 mL 1.1479 mL 2.2958 mL 5.7394 mL
20 mM 0.1722 mL 0.8609 mL 1.7218 mL 4.3046 mL
25 mM 0.1377 mL 0.6887 mL 1.3775 mL 3.4436 mL
30 mM 0.1148 mL 0.5739 mL 1.1479 mL 2.8697 mL
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4-Hydroxyestrone-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-Hydroxyestrone-d481586-98-34-OHE1-d4Endogenous MetaboliteIsotope-Labeled CompoundsInhibitorinhibitorinhibit

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