4'-(Methylsulfonyl)acetophenone

Name: 4'-(Methylsulfonyl)acetophenone
Brand: MedChemExpress
SKU: HY-34392
Rating: 4.5 (1 reviews)

Cat. No.: HY-34392 Purity: 99.43%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

p-Methylsulfonylacetophenone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

4'-(Methylsulfonyl)acetophenone Chemical Structure

CAS No. : 10297-73-1

Size	Price	Stock	Quantity
Free Sample (0.1 - 0.5 mg)		Apply Now
1 g	USD 30	In-stock	Estimated Time of Arrival: December 31
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10 g		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
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Description

p-Methylsulfonylacetophenone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

In Vitro

An impurity of Etoricoxib

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

198.24

Formula

C₉H₁₀O₃S

CAS No.

10297-73-1

Appearance

Solid

Color

White to off-white

SMILES

CC(C1=CC=C(S(=O)(C)=O)C=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (504.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.0444 mL	25.2220 mL	50.4439 mL
5 mM	1.0089 mL	5.0444 mL	10.0888 mL
10 mM	0.5044 mL	2.5222 mL	5.0444 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (12.61 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 2

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (12.61 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.43%

Select Batch:

Data Sheet (248 KB) SDS (393 KB)

COA (252 KB) HNMR (114 KB) RP-HPLC (345 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.0444 mL	25.2220 mL	50.4439 mL	126.1098 mL
	5 mM	1.0089 mL	5.0444 mL	10.0888 mL	25.2220 mL
	10 mM	0.5044 mL	2.5222 mL	5.0444 mL	12.6110 mL
	15 mM	0.3363 mL	1.6815 mL	3.3629 mL	8.4073 mL
	20 mM	0.2522 mL	1.2611 mL	2.5222 mL	6.3055 mL
	25 mM	0.2018 mL	1.0089 mL	2.0178 mL	5.0444 mL
	30 mM	0.1681 mL	0.8407 mL	1.6815 mL	4.2037 mL
	40 mM	0.1261 mL	0.6305 mL	1.2611 mL	3.1527 mL
	50 mM	0.1009 mL	0.5044 mL	1.0089 mL	2.5222 mL
	60 mM	0.0841 mL	0.4204 mL	0.8407 mL	2.1018 mL
	80 mM	0.0631 mL	0.3153 mL	0.6305 mL	1.5764 mL
	100 mM	0.0504 mL	0.2522 mL	0.5044 mL	1.2611 mL