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  4. 4-Methylumbelliferyl-α-D-Glucopyranoside

4-Methylumbelliferyl-α-D-Glucopyranoside  (Synonyms: 4-Methylumbelliferyl-α-D-Glucose; 4-Methylumbelliferyl-α-D-Glucoside; 4-MU-α-D-Glucopyranoside)

Cat. No.: HY-137873
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4-Methylumbelliferyl-α-D-Glucopyranoside (4-Methylumbelliferyl-α-D-Glucose; 4-Methylumbelliferyl-α-D-Glucoside) is a fluorogenic substrate for α-glucosidase. 4-Methylumbelliferyl-α-D-glucopyranoside is cleaved by α-glucosidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases. 4-Methylumbelliferyl-α-D-glucopyranoside has been used to quantify α-glucosidase activity in infant blood spot samples as a biomarker of Fabry and Pompe diseases, lysosomal storage disorders characterized by a deficiency in the enzyme.

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4-Methylumbelliferyl-α-D-Glucopyranoside Chemical Structure

4-Methylumbelliferyl-α-D-Glucopyranoside Chemical Structure

CAS No. : 17833-43-1

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4-Methylumbelliferyl-α-D-Glucopyranoside Related Antibodies

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Description

4-Methylumbelliferyl-α-D-Glucopyranoside (4-Methylumbelliferyl-α-D-Glucose; 4-Methylumbelliferyl-α-D-Glucoside) is a fluorogenic substrate for α-glucosidase. 4-Methylumbelliferyl-α-D-glucopyranoside is cleaved by α-glucosidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases. 4-Methylumbelliferyl-α-D-glucopyranoside has been used to quantify α-glucosidase activity in infant blood spot samples as a biomarker of Fabry and Pompe diseases, lysosomal storage disorders characterized by a deficiency in the enzyme.

Molecular Weight

338.31

Formula

C16H18O8
CAS No.
SMILES

O=C1C=C(C)C2=CC=C(O[C@@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)C=C2O1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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4-Methylumbelliferyl-α-D-Glucopyranoside Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

4-Methylumbelliferyl-α-D-Glucopyranoside17833-43-14-Methylumbelliferyl-α-D-Glucose 4-Methylumbelliferyl-α-D-Glucoside 4-MU-α-D-GlucopyranosideFluorescent DyeInhibitorinhibitorinhibit

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