5-Formyl-2'-deoxyuridine

Cat. No.: HY-W341499 Purity: 99.64%: FAQs
Data Sheet SDS COA Handling Instructions

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5-Formyl-2'-deoxyuridine is a product formed when the 5-methyl group of thymine in DNA undergoes oxidation due to exposure to gamma radiation or certain chemical agents. Serving as a biomarker of oxidative DNA damage, 5-formyl-2'-deoxyuridine is employed in investigations of DNA damage and repair mechanisms. Additionally, 5-Formyl-2'-deoxyuridine can be used in studies involving chemically crosslinking with peptides derived from the RecA protein.

For research use only. We do not sell to patients.

5-Formyl-2'-deoxyuridine Chemical Structure

CAS No. : 4494-26-2

Size	Price	Stock	Quantity
5 mg	USD 30	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Description

Molecular Weight

256.21

Formula

C₁₀H₁₂N₂O₆

CAS No.

4494-26-2

Appearance

Solid

Color

White to off-white

SMILES

OC[C@@H]1[C@@H](O)C[C@H](N2C=C(C=O)C(NC2=O)=O)O1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 200 mg/mL (780.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.9030 mL	19.5152 mL	39.0305 mL
5 mM	0.7806 mL	3.9030 mL	7.8061 mL
10 mM	0.3903 mL	1.9515 mL	3.9030 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.64%

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Data Sheet (274 KB) SDS (393 KB)

COA (253 KB) HNMR (253 KB) LCMS (91 KB)

Handling Instructions (2659 KB)

References

[1]. Sugiyama T, et al. Chemical cross-linking of peptides derived from RecA with single-stranded oligonucleotides containing 5-formyl-2′-deoxyuridine[J]. Nucleosides, Nucleotides and Nucleic Acids, 2001, 20(4-7): 1079-1083. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.9030 mL	19.5152 mL	39.0305 mL	97.5762 mL
	5 mM	0.7806 mL	3.9030 mL	7.8061 mL	19.5152 mL
	10 mM	0.3903 mL	1.9515 mL	3.9030 mL	9.7576 mL
	15 mM	0.2602 mL	1.3010 mL	2.6020 mL	6.5051 mL
	20 mM	0.1952 mL	0.9758 mL	1.9515 mL	4.8788 mL
	25 mM	0.1561 mL	0.7806 mL	1.5612 mL	3.9030 mL
	30 mM	0.1301 mL	0.6505 mL	1.3010 mL	3.2525 mL
	40 mM	0.0976 mL	0.4879 mL	0.9758 mL	2.4394 mL
	50 mM	0.0781 mL	0.3903 mL	0.7806 mL	1.9515 mL
	60 mM	0.0651 mL	0.3253 mL	0.6505 mL	1.6263 mL
	80 mM	0.0488 mL	0.2439 mL	0.4879 mL	1.2197 mL
	100 mM	0.0390 mL	0.1952 mL	0.3903 mL	0.9758 mL