2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis Nucleoside Antimetabolite/Analog
  4. 5'-O-DMT-dT

5'-O-DMT-dT  (Synonyms: 5'-O-(4,4'-Dimethoxytrityl)thymidine)

Cat. No.: HY-20140 Purity: 99.09%
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5'-O-DMT-dT (5'-O-(4,4'-Dimethoxytrityl)thymidine) is a nucleoside derivative which can be used in the preparation of oligonucleotides.

For research use only. We do not sell to patients.

5'-O-DMT-dT Chemical Structure

5'-O-DMT-dT Chemical Structure

CAS No. : 40615-39-2

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5'-O-DMT-dT Related Antibodies

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Description

5'-O-DMT-dT (5'-O-(4,4'-Dimethoxytrityl)thymidine) is a nucleoside derivative which can be used in the preparation of oligonucleotides[1].

Molecular Weight

544.59

Formula

C31H32N2O7
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1C[C@H](N2C(NC(C(C)=C2)=O)=O)O[C@@H]1COC(C3=CC=C(OC)C=C3)(C4=CC=CC=C4)C5=CC=C(OC)C=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (183.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8362 mL 9.1812 mL 18.3624 mL
5 mM 0.3672 mL 1.8362 mL 3.6725 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8362 mL 9.1812 mL 18.3624 mL 45.9061 mL
5 mM 0.3672 mL 1.8362 mL 3.6725 mL 9.1812 mL
10 mM 0.1836 mL 0.9181 mL 1.8362 mL 4.5906 mL
15 mM 0.1224 mL 0.6121 mL 1.2242 mL 3.0604 mL
20 mM 0.0918 mL 0.4591 mL 0.9181 mL 2.2953 mL
25 mM 0.0734 mL 0.3672 mL 0.7345 mL 1.8362 mL
30 mM 0.0612 mL 0.3060 mL 0.6121 mL 1.5302 mL
40 mM 0.0459 mL 0.2295 mL 0.4591 mL 1.1477 mL
50 mM 0.0367 mL 0.1836 mL 0.3672 mL 0.9181 mL
60 mM 0.0306 mL 0.1530 mL 0.3060 mL 0.7651 mL
80 mM 0.0230 mL 0.1148 mL 0.2295 mL 0.5738 mL
100 mM 0.0184 mL 0.0918 mL 0.1836 mL 0.4591 mL
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5'-O-DMT-dT Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5'-O-DMT-dT40615-39-25'-O-(4,4'-Dimethoxytrityl)thymidineDNA/RNA SynthesisNucleoside Antimetabolite/AnalognucleosideoligonucleotidesInhibitorinhibitorinhibit

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