5(6)-TAMRA SE  (Synonyms: 5(6)-Carboxytetramethylrhodamine N-succinimidyl ester)

5(6)-TAMRA SE is a fluorescent dye that emits red fluorescence. 5(6)-TAMRA SE binds to oligonucleotides and is used in DNA sequencing. 5(6)-TAMRA SE can be used in cancer research^[1][2][3][4].

5(6)-TAMRA SE (red fluorescent) labels splenocytes from B16-FL tumor-carrying B6 or CCR9-deficient mice^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

527.53

C₂₉H₂₅N₃O₇

246256-50-8

Solid

Purple to purplish red

580

565

[O-]C(C(C=C(C(ON(C(CC1)=O)C1=O)=O)C=C2)=C2C3=C(C=CC(N(C)C)=C4)C4=[O+]C5=C3C=CC(N(C)C)=C5)=O.O=C(C6=CC(C7=C(C=CC(N(C)C)=C8)C8=[O+]C9=C7C=CC(N(C)C)=C9)=C(C=C6)C([O-])=O)ON(C(CC%10)=O)C%10=O

Room temperature in continental US; may vary elsewhere.

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

• [1]. Fuller ME, et al. Application of a vital fluorescent staining method for simultaneous, near-real-time concentration monitoring of two bacterial strains in an Atlantic coastal plain aquifer in Oyster, Virginia. Appl Environ Microbiol. 2004 Mar;70(3):1680-7.  [Content Brief]

  [2]. Brunner A, et al. Labelling peptides with fluorescent probes for incorporation into degradable polymers. Eur J Pharm Biopharm. 1998 May;45(3):265-73.  [Content Brief]

  [3]. Jiang M, et al. Design and synthesis of new acid cleavable linkers for DNA sequencing by synthesis. Nucleosides Nucleotides Nucleic Acids. 2014;33(12):774-85.  [Content Brief]

  [4]. Wendland M, et al. CCR9 is a homing receptor for plasmacytoid dendritic cells to the small intestine. Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6347-52.  [Content Brief]