6-(4-Methoxyphenyl)pyridazin-3-amine

Cat. No.: HY-W025443 Purity: 97.31%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

6-(4-Methoxyphenyl)pyridazin-3-amine is an aminopyridazine derivative, and can be used for the synthesis of SR 95103. SR 95103 is a selective and competitive GABA-A receptor antagonist.

For research use only. We do not sell to patients.

6-(4-Methoxyphenyl)pyridazin-3-amine Chemical Structure

CAS No. : 4776-87-8

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	Get quote	Estimated Time of Arrival: December 31
10 mg	Get quote	Estimated Time of Arrival: December 31
25 mg	Get quote	Estimated Time of Arrival: December 31
50 mg	Get quote	Estimated Time of Arrival: December 31
100 mg	Get quote	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Purity & Documentation
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Description

6-(4-Methoxyphenyl)pyridazin-3-amine is an aminopyridazine derivative, and can be used for the synthesis of SR 95103. SR 95103 is a selective and competitive GABA-A receptor antagonist^[1].

Molecular Weight

201.23

Formula

C₁₁H₁₁N₃O

CAS No.

4776-87-8

Appearance

Solid

Color

Light brown to brown

SMILES

COC1=CC=C(C2=NN=C(C=C2)N)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 15 mg/mL (74.54 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.9695 mL	24.8473 mL	49.6946 mL
5 mM	0.9939 mL	4.9695 mL	9.9389 mL
10 mM	0.4969 mL	2.4847 mL	4.9695 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 97.31%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (246 KB) HNMR (121 KB) LCMS (102 KB)

Handling Instructions (2659 KB)

References

[1]. Wermuth CG, et al. Synthesis and structure-activity relationships of a series of aminopyridazine derivatives of gamma-aminobutyric acid acting as selective GABA-A antagonists. J Med Chem. 1987 Feb;30(2):239-49. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.9695 mL	24.8473 mL	49.6946 mL	124.2366 mL
	5 mM	0.9939 mL	4.9695 mL	9.9389 mL	24.8473 mL
	10 mM	0.4969 mL	2.4847 mL	4.9695 mL	12.4237 mL
	15 mM	0.3313 mL	1.6565 mL	3.3130 mL	8.2824 mL
	20 mM	0.2485 mL	1.2424 mL	2.4847 mL	6.2118 mL
	25 mM	0.1988 mL	0.9939 mL	1.9878 mL	4.9695 mL
	30 mM	0.1656 mL	0.8282 mL	1.6565 mL	4.1412 mL
	40 mM	0.1242 mL	0.6212 mL	1.2424 mL	3.1059 mL
	50 mM	0.0994 mL	0.4969 mL	0.9939 mL	2.4847 mL
	60 mM	0.0828 mL	0.4141 mL	0.8282 mL	2.0706 mL