2. Others Metabolic Enzyme/Protease
  3. Drug Metabolite Isotope-Labeled Compounds
  4. 6-Hydroxy Chlorzoxazone-15N,d2

6-Hydroxy Chlorzoxazone-15N,d2 is the 15N and deuterium labeled 6-Hydroxy Chlorzoxazone (HY-W016221).

For research use only. We do not sell to patients.

6-Hydroxy Chlorzoxazone-<sup>15</sup>N,d<sub>2</sub> Chemical Structure

6-Hydroxy Chlorzoxazone-15N,d2 Chemical Structure

CAS No. : 1784060-40-7

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Other Forms of 6-Hydroxy Chlorzoxazone-15N,d2:

6-Hydroxy Chlorzoxazone-15N,d2 Related Antibodies

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Description

6-Hydroxy Chlorzoxazone-15N,d2 is the 15N and deuterium labeled 6-Hydroxy Chlorzoxazone (HY-W016221)[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

6-Hydroxy Chlorzoxazone-15N,d2 Related Antibodies
Molecular Weight

188.57

Formula

C7H2D2Cl15NO3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

ClC1=C([2H])C([15N]=C2O)=C(O2)C([2H])=C1O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (530.31 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.3031 mL 26.5154 mL 53.0307 mL
5 mM 1.0606 mL 5.3031 mL 10.6061 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.3031 mL 26.5154 mL 53.0307 mL 132.5768 mL
5 mM 1.0606 mL 5.3031 mL 10.6061 mL 26.5154 mL
10 mM 0.5303 mL 2.6515 mL 5.3031 mL 13.2577 mL
15 mM 0.3535 mL 1.7677 mL 3.5354 mL 8.8385 mL
20 mM 0.2652 mL 1.3258 mL 2.6515 mL 6.6288 mL
25 mM 0.2121 mL 1.0606 mL 2.1212 mL 5.3031 mL
30 mM 0.1768 mL 0.8838 mL 1.7677 mL 4.4192 mL
40 mM 0.1326 mL 0.6629 mL 1.3258 mL 3.3144 mL
50 mM 0.1061 mL 0.5303 mL 1.0606 mL 2.6515 mL
60 mM 0.0884 mL 0.4419 mL 0.8838 mL 2.2096 mL
80 mM 0.0663 mL 0.3314 mL 0.6629 mL 1.6572 mL
100 mM 0.0530 mL 0.2652 mL 0.5303 mL 1.3258 mL
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6-Hydroxy Chlorzoxazone-15N,d2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-Hydroxy Chlorzoxazone-15N,d21784060-40-7Drug MetaboliteIsotope-Labeled CompoundsIsotopeLabeledInhibitorinhibitorinhibit

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