2. Cell Cycle/DNA Damage Autophagy Metabolic Enzyme/Protease
  3. Nucleoside Antimetabolite/Analog Autophagy Endogenous Metabolite
  4. 6-Mercaptopurine-13C2,15N

6-Mercaptopurine-13C2,15N  (Synonyms: Mercaptopurine-13C2,15N; 6-MP-13C2,15N)

Cat. No.: HY-13677S1 Purity: ≥96.0%
COA Handling Instructions

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6-Mercaptopurine-13C2,15N is the 13C- and 15N-labeled 6-Mercaptopurine. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent.

For research use only. We do not sell to patients.

6-Mercaptopurine-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N Chemical Structure

6-Mercaptopurine-13C2,15N Chemical Structure

CAS No. : 1190008-04-8

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Based on 1 publication(s) in Google Scholar

Other Forms of 6-Mercaptopurine-13C2,15N:

6-Mercaptopurine-13C2,15N Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

6-Mercaptopurine-13C2,15N is the 13C- and 15N-labeled 6-Mercaptopurine. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

6-Mercaptopurine-13C2,15N Related Antibodies
Molecular Weight

155.16

Formula

C313C2H4N315NS
CAS No.
Unlabeled CAS

50-44-2
Appearance

Solid

Color

White to off-white

SMILES

SC1=C2[13C](N[13CH]=[15N]2)=NC=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 35.71 mg/mL (230.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 35.71 mg/mL (230.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.4450 mL 32.2248 mL 64.4496 mL
5 mM 1.2890 mL 6.4450 mL 12.8899 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥96.0%

COA (256 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 6.4450 mL 32.2248 mL 64.4496 mL 161.1240 mL
5 mM 1.2890 mL 6.4450 mL 12.8899 mL 32.2248 mL
10 mM 0.6445 mL 3.2225 mL 6.4450 mL 16.1124 mL
15 mM 0.4297 mL 2.1483 mL 4.2966 mL 10.7416 mL
20 mM 0.3222 mL 1.6112 mL 3.2225 mL 8.0562 mL
25 mM 0.2578 mL 1.2890 mL 2.5780 mL 6.4450 mL
30 mM 0.2148 mL 1.0742 mL 2.1483 mL 5.3708 mL
40 mM 0.1611 mL 0.8056 mL 1.6112 mL 4.0281 mL
50 mM 0.1289 mL 0.6445 mL 1.2890 mL 3.2225 mL
60 mM 0.1074 mL 0.5371 mL 1.0742 mL 2.6854 mL
80 mM 0.0806 mL 0.4028 mL 0.8056 mL 2.0140 mL
100 mM 0.0644 mL 0.3222 mL 0.6445 mL 1.6112 mL
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6-Mercaptopurine-13C2,15N Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-Mercaptopurine-13C2,15N1190008-04-8Mercaptopurine-13C2,15N6-MP-13C2,15NNucleoside Antimetabolite/AnalogAutophagyEndogenous MetaboliteInhibitorinhibitorinhibit

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