2. Others
  3. Isotope-Labeled Compounds
  4. 6-(γ,γ-Dimethylallylamino)purine-d6

6-(γ,γ-Dimethylallylamino)purine-d6  (Synonyms: N6-(2-lsopentenyl)adenine-d6)

Cat. No.: HY-112103S Purity: ≥98.0%
COA Handling Instructions

Molarity Calculator

For research use only. We do not sell to patients.

6-(γ,γ-Dimethylallylamino)purine-d<sub>6</sub> Chemical Structure

6-(γ,γ-Dimethylallylamino)purine-d6 Chemical Structure

CAS No. : 175733-28-5

Size Price Stock Quantity
1 mg USD 1650 In-stock
5 mg   Get quote  
10 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of 6-(γ,γ-Dimethylallylamino)purine-d6:

6-(γ,γ-Dimethylallylamino)purine-d6 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description
In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Derivative UV spectroscopic data show that the plant growth substances 6-(γ,γ-Dimethylallylamino)purine (N6-(delta 2-isopentenyl) adenine, i6Ade)and indolylacetic acid (IAA) can bind to the yeast alcohol dehydrogenase (ADH) and affect coenzyme-enzyme binding. At fixed ethanol concentrations (27.8 and 111.1 mM) and varying NAD+ concentrations (0.033-2 mM), as well as at fixed levels of coenzyme (0.67 and 2 mM), and at varying concentrations of ethanol (1.4-111.1 mM), the rate of ethanol oxidation is significantly inhibited by i6Ade and IAA. The kinetics of the ADH reaction is affected by two inhibition constants (Ki and Ki') which correspond to the dissociation constants of complexes EI and ESI, respectively. For i6Ade the Ki=0.52±0.06 mM and Ki'=0.74±0.07 mM, and for IAA the Ki=0.88±0.03 mM and Ki'=0.99±0.02 mM[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

6-(γ,γ-Dimethylallylamino)purine-d6 Related Antibodies
Molecular Weight

209.28

Formula

C10H7D6N5
CAS No.
Unlabeled CAS

2365-40-4
Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])/C(C([2H])([2H])[2H])=C/CNC1=C2C(N=CN2)=NC=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 60 mg/mL (286.70 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.7783 mL 23.8914 mL 47.7829 mL
5 mM 0.9557 mL 4.7783 mL 9.5566 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (252 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.7783 mL 23.8914 mL 47.7829 mL 119.4572 mL
5 mM 0.9557 mL 4.7783 mL 9.5566 mL 23.8914 mL
10 mM 0.4778 mL 2.3891 mL 4.7783 mL 11.9457 mL
15 mM 0.3186 mL 1.5928 mL 3.1855 mL 7.9638 mL
20 mM 0.2389 mL 1.1946 mL 2.3891 mL 5.9729 mL
25 mM 0.1911 mL 0.9557 mL 1.9113 mL 4.7783 mL
30 mM 0.1593 mL 0.7964 mL 1.5928 mL 3.9819 mL
40 mM 0.1195 mL 0.5973 mL 1.1946 mL 2.9864 mL
50 mM 0.0956 mL 0.4778 mL 0.9557 mL 2.3891 mL
60 mM 0.0796 mL 0.3982 mL 0.7964 mL 1.9910 mL
80 mM 0.0597 mL 0.2986 mL 0.5973 mL 1.4932 mL
100 mM 0.0478 mL 0.2389 mL 0.4778 mL 1.1946 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

6-(γ,γ-Dimethylallylamino)purine-d6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-(γ,γ-Dimethylallylamino)purine-d6175733-28-5N6-(2-lsopentenyl)adenine-d6Isotope-Labeled CompoundsInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
6-(γ,γ-Dimethylallylamino)purine-d6
Cat. No.:
HY-112103S
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.