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  4. 7-Aminodeacetoxycephalosporanic acid

7-Aminodeacetoxycephalosporanic acid  (Synonyms: 7-ADCA)

Cat. No.: HY-W014217 Purity: ≥98.0%
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7-Aminodeacetoxycephalosporanic acid (7-ADCA) is a key intermediate in the synthesis of cephalosporins.

For research use only. We do not sell to patients.

7-Aminodeacetoxycephalosporanic acid Chemical Structure

7-Aminodeacetoxycephalosporanic acid Chemical Structure

CAS No. : 22252-43-3

Size Price Stock Quantity
500 mg In-stock
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5 g   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of 7-Aminodeacetoxycephalosporanic acid:

7-Aminodeacetoxycephalosporanic acid Related Antibodies

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Description

7-Aminodeacetoxycephalosporanic acid (7-ADCA) is a key intermediate in the synthesis of cephalosporins[1].

In Vitro

Key intermediates in the synthesis of cephalosporins are 7-Aminocephalosporanic acid (HY-B1434) and 7-Aminodesacetoxycephalosporanic acid (7-ADCA). 7-Aminodesacetoxycephalosporanic acid (7-ADCA) is produced from Penicillin G (HY-N7139) by Penicillium chrysogenum by a process that comprises several polluting chemical steps, followed by enzymatic deacylation by using penicillin acylase[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

7-Aminodeacetoxycephalosporanic acid Related Antibodies
Molecular Weight

214.25

Formula

C8H10N2O3S
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1N2[C@]([C@@H]1N)([H])SCC(C)=C2C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

NH4OH : 50 mg/mL (233.38 mM; ultrasonic and adjust pH to 9 with NH4OH)

25 % w/v ammonia solution : 50 mg/mL (233.38 mM; ultrasonic and adjust pH to 9 with NH4OH)

H2O : 41.67 mg/mL (194.50 mM; ultrasonic and adjust pH to 10 with NaOH)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.6675 mL 23.3377 mL 46.6753 mL
5 mM 0.9335 mL 4.6675 mL 9.3351 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / NH4OH / 25 % w/v ammonia solution 1 mM 4.6675 mL 23.3377 mL 46.6753 mL 116.6883 mL
5 mM 0.9335 mL 4.6675 mL 9.3351 mL 23.3377 mL
10 mM 0.4668 mL 2.3338 mL 4.6675 mL 11.6688 mL
15 mM 0.3112 mL 1.5558 mL 3.1117 mL 7.7792 mL
20 mM 0.2334 mL 1.1669 mL 2.3338 mL 5.8344 mL
25 mM 0.1867 mL 0.9335 mL 1.8670 mL 4.6675 mL
30 mM 0.1556 mL 0.7779 mL 1.5558 mL 3.8896 mL
40 mM 0.1167 mL 0.5834 mL 1.1669 mL 2.9172 mL
50 mM 0.0934 mL 0.4668 mL 0.9335 mL 2.3338 mL
60 mM 0.0778 mL 0.3890 mL 0.7779 mL 1.9448 mL
80 mM 0.0583 mL 0.2917 mL 0.5834 mL 1.4586 mL
100 mM 0.0467 mL 0.2334 mL 0.4668 mL 1.1669 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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7-Aminodeacetoxycephalosporanic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

7-Aminodeacetoxycephalosporanic acid22252-43-37-ADCADrug IntermediateDrug IintermediateInhibitorinhibitorinhibit

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