7H-Purine-2,6-diamine

Name: 7H-Purine-2,6-diamine
Brand: MedChemExpress
SKU: HY-W013631
Rating: 4.5 (1 reviews)

Cat. No.: HY-W013631 Purity: 99.99%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

7H-Purine-2,6-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

7H-Purine-2,6-diamine Chemical Structure

CAS No. : 1904-98-9

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Free Sample (0.1 - 0.5 mg)		Apply Now
5 g	USD 30	In-stock	Estimated Time of Arrival: December 31
25 g	USD 90	In-stock	Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
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Description

7H-Purine-2,6-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF-HSB-2	CC₅₀	> 20 μM Compound: DAP	Cytotoxicity against human HSB2 cells after 7 days by Cell-Titer Glo assay Cytotoxicity against human HSB2 cells after 7 days by Cell-Titer Glo assay	[PMID: 22607883]
HFF	IC₅₀	> 300 μM Compound: DAP	Antiviral activity against HSV-1 infected in human HFF cells assessed as reduction in cytopathic effect after 3 days by crystal violet staining Antiviral activity against HSV-1 infected in human HFF cells assessed as reduction in cytopathic effect after 3 days by crystal violet staining	[PMID: 22607883]
HFF	IC₅₀	> 300 μM Compound: DAP	Antiviral activity against HSV-2 infected in human HFF cells assessed as reduction in cytopathic effect after 3 days by crystal violet staining Antiviral activity against HSV-2 infected in human HFF cells assessed as reduction in cytopathic effect after 3 days by crystal violet staining	[PMID: 22607883]
HFF	IC₅₀	> 300 μM Compound: DAP	Antiviral activity against VZV infected in human HFF cells assessed as reduction in cytopathic effect after 7 days by crystal violet staining Antiviral activity against VZV infected in human HFF cells assessed as reduction in cytopathic effect after 7 days by crystal violet staining	[PMID: 22607883]
HFF	CC₅₀	> 300 μM Compound: DAP	Cytotoxicity against human HFF cells after 3 to 8 days by crystal voilet staining Cytotoxicity against human HFF cells after 3 to 8 days by crystal voilet staining	[PMID: 22607883]
HFF	IC₅₀	> 300 μM Compound: DAP	Antiviral activity against HCMV infected in human HFF cells assessed as reduction in cytopathic effect after 8 days by plaque reduction assay Antiviral activity against HCMV infected in human HFF cells assessed as reduction in cytopathic effect after 8 days by plaque reduction assay	[PMID: 22607883]
MOLT-3	CC₅₀	> 20 μM Compound: DAP	Cytotoxicity against human MOLT3 cells after 7 days by Cell-Titer Glo assay Cytotoxicity against human MOLT3 cells after 7 days by Cell-Titer Glo assay	[PMID: 22607883]
MOLT-3	IC₅₀	16 μM Compound: DAP	Antiviral activity against HHV-6B infected in human Molt3 cells assessed as reduction in viral DNA after 7 days by hybridization assay Antiviral activity against HHV-6B infected in human Molt3 cells assessed as reduction in viral DNA after 7 days by hybridization assay	[PMID: 22607883]

In Vitro

2,6-Diaminopurine is a compound used to study leukemia.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

150.14

Formula

C₅H₆N₆

CAS No.

1904-98-9

Appearance

Solid

Color

Off-white to yellow

SMILES

NC1=NC(N)=C2NC=NC2=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 58.33 mg/mL (388.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.6604 mL	33.3022 mL	66.6045 mL
5 mM	1.3321 mL	6.6605 mL	13.3209 mL
10 mM	0.6660 mL	3.3302 mL	6.6605 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.99%

Select Batch:

Data Sheet (245 KB) SDS (557 KB)

COA (250 KB) HNMR (117 KB) RP-HPLC (187 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.6605 mL	33.3023 mL	66.6045 mL	166.5113 mL
	5 mM	1.3321 mL	6.6605 mL	13.3209 mL	33.3023 mL
	10 mM	0.6660 mL	3.3302 mL	6.6605 mL	16.6511 mL
	15 mM	0.4440 mL	2.2202 mL	4.4403 mL	11.1008 mL
	20 mM	0.3330 mL	1.6651 mL	3.3302 mL	8.3256 mL
	25 mM	0.2664 mL	1.3321 mL	2.6642 mL	6.6605 mL
	30 mM	0.2220 mL	1.1101 mL	2.2202 mL	5.5504 mL
	40 mM	0.1665 mL	0.8326 mL	1.6651 mL	4.1628 mL
	50 mM	0.1332 mL	0.6660 mL	1.3321 mL	3.3302 mL
	60 mM	0.1110 mL	0.5550 mL	1.1101 mL	2.7752 mL
	80 mM	0.0833 mL	0.4163 mL	0.8326 mL	2.0814 mL
	100 mM	0.0666 mL	0.3330 mL	0.6660 mL	1.6651 mL