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  4. 8-Bromo-AMP

8-Bromo-AMP  (Synonyms: 8-Bromoadenosine 5'-monophosphate; 8-Bromoadenylic acid)

Cat. No.: HY-134266 Purity: 98.81%
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8-Bromo-AMP (8-Bromoadenosine 5'-monophosphate) is a membrane permeable cAMP analogue. 8-Bromo-AMP can improve the ability of the heart to recover from ischemia and reperfusion by increasing the levels of ATP, ADP, and total adenine nucleotides.

For research use only. We do not sell to patients.

8-Bromo-AMP Chemical Structure

8-Bromo-AMP Chemical Structure

CAS No. : 23567-96-6

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5 mg USD 250 In-stock
10 mg USD 400 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of 8-Bromo-AMP:

8-Bromo-AMP Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE 8-Bromo-AMP

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  • Purity & Documentation

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Description

8-Bromo-AMP (8-Bromoadenosine 5'-monophosphate) is a membrane permeable cAMP analogue. 8-Bromo-AMP can improve the ability of the heart to recover from ischemia and reperfusion by increasing the levels of ATP, ADP, and total adenine nucleotides[1][2].

Molecular Weight

426.12

Formula

C10H13BrN5O7P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=P(O)(OC[C@@H]1[C@H]([C@H]([C@H](N2C(Br)=NC3=C(N=CN=C32)N)O1)O)O)O
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (293.34 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3468 mL 11.7338 mL 23.4676 mL
5 mM 0.4694 mL 2.3468 mL 4.6935 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 98.81%

COA (255 KB) LCMS (92 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.3468 mL 11.7338 mL 23.4676 mL 58.6689 mL
5 mM 0.4694 mL 2.3468 mL 4.6935 mL 11.7338 mL
10 mM 0.2347 mL 1.1734 mL 2.3468 mL 5.8669 mL
15 mM 0.1565 mL 0.7823 mL 1.5645 mL 3.9113 mL
20 mM 0.1173 mL 0.5867 mL 1.1734 mL 2.9334 mL
25 mM 0.0939 mL 0.4694 mL 0.9387 mL 2.3468 mL
30 mM 0.0782 mL 0.3911 mL 0.7823 mL 1.9556 mL
40 mM 0.0587 mL 0.2933 mL 0.5867 mL 1.4667 mL
50 mM 0.0469 mL 0.2347 mL 0.4694 mL 1.1734 mL
60 mM 0.0391 mL 0.1956 mL 0.3911 mL 0.9778 mL
80 mM 0.0293 mL 0.1467 mL 0.2933 mL 0.7334 mL
100 mM 0.0235 mL 0.1173 mL 0.2347 mL 0.5867 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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8-Bromo-AMP Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

8-Bromo-AMP23567-96-68-Bromoadenosine 5'-monophosphate 8-Bromoadenylic acidOtherscAMP analogueATPADPadeninenucleotidesInhibitorinhibitorinhibit

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