2. Natural Products
  3. Plants Terpenoids
  4. Podocarpaceae Diterpenoids
  5. Podocarpus macrophyllus (Thunb.) Sweet
  6. 9,13-Epidioxy-8(14)-abieten-18-oic acid

9,13-Epidioxy-8(14)-abieten-18-oic acid is a Diterpenoids product that can be isolated from the heartwoods of Podocarpus macrophyllus.

For research use only. We do not sell to patients.

9,13-Epidioxy-8(14)-abieten-18-oic acid Chemical Structure

9,13-Epidioxy-8(14)-abieten-18-oic acid Chemical Structure

CAS No. : 5309-35-3

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9,13-Epidioxy-8(14)-abieten-18-oic acid Related Antibodies

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Description

9,13-Epidioxy-8(14)-abieten-18-oic acid is a Diterpenoids product that can be isolated from the heartwoods of Podocarpus macrophyllus[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 10 μM
Compound: 15
Cytotoxicity in human A549 cells by SRB assay
Cytotoxicity in human A549 cells by SRB assay
[PMID: 26812172]
BV-2 IC50
34.7 μM
Compound: 4
Inhibition of LPS-induced NO production in mouse BV2 cells after 20 hrs by Griess assay
Inhibition of LPS-induced NO production in mouse BV2 cells after 20 hrs by Griess assay
[PMID: 27989668]
BV-2 IC50
57.3 μM
Compound: 15
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess assay
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess assay
[PMID: 26812172]
HCT-116 IC50
> 10 μM
Compound: 15
Cytotoxicity in human HCT116 cells by SRB assay
Cytotoxicity in human HCT116 cells by SRB assay
[PMID: 26812172]
SK-MEL-2 IC50
> 10 μM
Compound: 15
Cytotoxicity in human SK-MEL-2 cells by SRB assay
Cytotoxicity in human SK-MEL-2 cells by SRB assay
[PMID: 26812172]
SK-OV-3 IC50
> 10 μM
Compound: 15
Cytotoxicity in human SKOV3 cells by SRB assay
Cytotoxicity in human SKOV3 cells by SRB assay
[PMID: 26812172]
Molecular Weight

334.45

Formula

C20H30O4
CAS No.
SMILES

C[C@@]12[C@@]34C(CC[C@@]1([H])[C@@](C)(CCC2)C(O)=O)=C[C@@](CC3)(OO4)C(C)C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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9,13-Epidioxy-8(14)-abieten-18-oic acid Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

9,13-Epidioxy-8(14)-abieten-18-oic acid5309-35-3OthersInhibitorinhibitorinhibit

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