2. Anti-infection
  3. Parasite Bacterial
  4. 9-Hydroxycalabaxanthone

9-Hydroxycalabaxanthone  (Synonyms: Xanthone I)

Cat. No.: HY-N2795 Purity: 99.14%
COA Handling Instructions

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9-Hydroxycalabaxanthone (Xanthone I) is a known xanthone isolated from Garcinia mangostana Linn. 9-Hydroxycalabaxanthone has quorum-sensing inhibitory, anti-microbial, and anti-malarial activities (IC50=1.2-1.5 μM).

For research use only. We do not sell to patients.

9-Hydroxycalabaxanthone Chemical Structure

9-Hydroxycalabaxanthone Chemical Structure

CAS No. : 35349-68-9

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5 mg USD 520 In-stock
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Based on 1 publication(s) in Google Scholar

9-Hydroxycalabaxanthone Related Antibodies

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

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Description

9-Hydroxycalabaxanthone (Xanthone I) is a known xanthone isolated from Garcinia mangostana Linn. 9-Hydroxycalabaxanthone has quorum-sensing inhibitory, anti-microbial, and anti-malarial activities (IC50=1.2-1.5 μM)[1].

IC50 & Target

Plasmodium

 

In Vitro

9-Hydroxycalabaxanthone inhibits the activities of 3D7 and K1 P. falciparum clones with IC50 values of 1.5 μM and 1.2 μM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

9-Hydroxycalabaxanthone Related Antibodies
Molecular Weight

408.44

Formula

C24H24O6
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C2=C(OC3=C1C(C/C=C(C)\C)=C(OC)C(O)=C3)C=C4C(C=CC(C)(C)O4)=C2O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (122.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4483 mL 12.2417 mL 24.4834 mL
5 mM 0.4897 mL 2.4483 mL 4.8967 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.14%

COA (251 KB) HNMR (131 KB) LCMS (245 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4483 mL 12.2417 mL 24.4834 mL 61.2085 mL
5 mM 0.4897 mL 2.4483 mL 4.8967 mL 12.2417 mL
10 mM 0.2448 mL 1.2242 mL 2.4483 mL 6.1209 mL
15 mM 0.1632 mL 0.8161 mL 1.6322 mL 4.0806 mL
20 mM 0.1224 mL 0.6121 mL 1.2242 mL 3.0604 mL
25 mM 0.0979 mL 0.4897 mL 0.9793 mL 2.4483 mL
30 mM 0.0816 mL 0.4081 mL 0.8161 mL 2.0403 mL
40 mM 0.0612 mL 0.3060 mL 0.6121 mL 1.5302 mL
50 mM 0.0490 mL 0.2448 mL 0.4897 mL 1.2242 mL
60 mM 0.0408 mL 0.2040 mL 0.4081 mL 1.0201 mL
80 mM 0.0306 mL 0.1530 mL 0.3060 mL 0.7651 mL
100 mM 0.0245 mL 0.1224 mL 0.2448 mL 0.6121 mL
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9-Hydroxycalabaxanthone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

9-Hydroxycalabaxanthone35349-68-9Xanthone IParasiteBacterialAntimalarial,quorum-sensingK1 P. falciparum3D7 P. falciparumInhibitorinhibitorinhibit

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