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  4. CY5-YNE

CY5-YNE  (Synonyms: Sulfo-Cyanine5-alkyne)

Cat. No.: HY-D0820 Purity: ≥95.0%
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CY5-YNE (Sulfo-Cyanine5-alkyne) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. CY5-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

For research use only. We do not sell to patients.

CY5-YNE Chemical Structure

CY5-YNE Chemical Structure

CAS No. : 1345823-20-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 336 In-stock
Solution
10 mM * 1 mL in DMSO USD 336 In-stock
Solid
5 mg USD 220 In-stock
10 mg USD 350 In-stock
25 mg USD 700 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

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Description

CY5-YNE (Sulfo-Cyanine5-alkyne) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. CY5-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Molecular Weight

693.87

Formula

C36H43N3O7S2
CAS No.
Appearance

Solid

Color

Grayish brown to reddish brown

Emission (Em)

670
Excitation (Ex)

645
SMILES

CC(/C(N1CCCCCC(NCC#C)=O)=C\C=C\C=C\C2=[N+](CC)C(C=CC(S(=O)([O-])=O)=C3)=C3C2(C)C)(C)C4=C1C=CC(S(=O)(O)=O)=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 43 mg/mL (61.97 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4412 mL 7.2060 mL 14.4119 mL
5 mM 0.2882 mL 1.4412 mL 2.8824 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4412 mL 7.2060 mL 14.4119 mL 36.0298 mL
5 mM 0.2882 mL 1.4412 mL 2.8824 mL 7.2060 mL
10 mM 0.1441 mL 0.7206 mL 1.4412 mL 3.6030 mL
15 mM 0.0961 mL 0.4804 mL 0.9608 mL 2.4020 mL
20 mM 0.0721 mL 0.3603 mL 0.7206 mL 1.8015 mL
25 mM 0.0576 mL 0.2882 mL 0.5765 mL 1.4412 mL
30 mM 0.0480 mL 0.2402 mL 0.4804 mL 1.2010 mL
40 mM 0.0360 mL 0.1801 mL 0.3603 mL 0.9007 mL
50 mM 0.0288 mL 0.1441 mL 0.2882 mL 0.7206 mL
60 mM 0.0240 mL 0.1201 mL 0.2402 mL 0.6005 mL
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CY5-YNE Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CY5-YNE1345823-20-2Sulfo-Cyanine5-alkyneFluorescent DyeInhibitorinhibitorinhibit

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