1. Others GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  2. Isotope-Labeled Compounds Histamine Receptor
  3. Cetirizine-d4 dihydrochloride

Cetirizine-d4 (dihydrochloride) is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].

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Cetirizine-d<sub>4</sub> dihydrochloride Chemical Structure

Cetirizine-d4 dihydrochloride Chemical Structure

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Description

Cetirizine-d4 (dihydrochloride) is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].

IC50 & Target

H1 Receptor

 

Molecular Weight

465.83

Formula

C21H23D4Cl3N2O3

Unlabeled CAS

83881-52-1

SMILES

ClC1=CC=C(C(N2CCN(C([2H])([2H])C([2H])([2H])OCC(O)=O)CC2)C3=CC=CC=C3)C=C1.Cl.Cl

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Cetirizine-d4 dihydrochloride
Cat. No.:
HY-17042AS
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