2. Membrane Transporter/Ion Channel Neuronal Signaling Autophagy
  3. nAChR Autophagy
  4. Cisatracurium besylate

Cisatracurium besylate  (Synonyms: 51W89 besylate; Cisatracurium besilate)

Cat. No.: HY-13596 Purity: ≥98.0%
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Cisatracurium besylate (51W89) is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.

For research use only. We do not sell to patients.

Cisatracurium besylate Chemical Structure

Cisatracurium besylate Chemical Structure

CAS No. : 96946-42-8

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 USD 88 In-stock
Solution
10 mM * 1 mL in Water USD 88 In-stock
Solid
25 mg USD 80 In-stock
50 mg USD 140 In-stock
100 mg USD 230 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of Cisatracurium besylate:

Cisatracurium besylate Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Cisatracurium besylate

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Cisatracurium besylate (51W89) is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.

IC50 & Target

AChR alpha-2[1][2].
In Vitro

Cisatracurium Besylate (51W89) is a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. It is a bisbenzyltetrahydroisoquinolinium agent with an intermediate duration of action. Cisatracurium Besylate (51W89) is one of the ten isomers of the parent molecule, atracurium. Moreover, cisatracurium represents approximately 15% of the atracurium mixture [1, 2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cisatracurium besylate Related Antibodies
Molecular Weight

1243.48

Formula

C65H82N2O18S2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(OCCCCCOC(CC[N@+]1(C)[C@H](CC2=CC=C(OC)C(OC)=C2)C3=C(C=C(OC)C(OC)=C3)CC1)=O)CC[N@+]4(C)[C@H](CC5=CC=C(OC)C(OC)=C5)C6=C(C=C(OC)C(OC)=C6)CC4.O=S(C7=CC=CC=C7)([O-])=O.O=S(C8=CC=CC=C8)([O-])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (40.21 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8042 mL 4.0210 mL 8.0419 mL
5 mM 0.1608 mL 0.8042 mL 1.6084 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (80.42 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.8042 mL 4.0210 mL 8.0419 mL 20.1049 mL
5 mM 0.1608 mL 0.8042 mL 1.6084 mL 4.0210 mL
10 mM 0.0804 mL 0.4021 mL 0.8042 mL 2.0105 mL
15 mM 0.0536 mL 0.2681 mL 0.5361 mL 1.3403 mL
20 mM 0.0402 mL 0.2010 mL 0.4021 mL 1.0052 mL
25 mM 0.0322 mL 0.1608 mL 0.3217 mL 0.8042 mL
30 mM 0.0268 mL 0.1340 mL 0.2681 mL 0.6702 mL
40 mM 0.0201 mL 0.1005 mL 0.2010 mL 0.5026 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Cisatracurium besylate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cisatracurium besylate96946-42-851W89 besylateCisatracuriumnAChRAutophagyNicotinic acetylcholine receptorsInhibitorinhibitorinhibit

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