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  6. FDA-Approved Anticancer Drug Library
FDA-Approved Anticancer Drug Library

Cat. No.: HY-L122

Cancer is the second leading cause of death worldwide and a serious threat to human health. Multiple treatments have been developed for cancer treatment, but new anti-cancer drugs still need to be developed urgently. Approved drugs, have well-characterized bioactivities, safety and bioavailability properties, will dramatically accelerate drug development.

MCE offers a unique collection of 1,445 approved drugs with anti-cancer activity, which can be used for discovery of new anti-cancer drugs or as positive compounds used for anti-cancer research.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Description & Advantages

•   A unique collection of 1,445 approved drugs with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS).

•   A useful tool for anti-cancer research and drug repurposing.

•   All compounds have been approved by the FDA, EMA and other countries.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

Product Details

Formulation:

A collection of 1,445 approved anti-cancer drugs supplied as pre-dissolved Solutions or Solid
Solution: 1,397 compounds supplied in 10 mM solution, 33 compounds supplied in 2 mM solution, 15 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice

Composition

HIV (55)

COX (53)

mAChR (34)

VEGFR (33)

EGFR (30)

PDGFR (25)

c-Kit (21)

FGFR (21)

Akt (15)

HSV (15)

nAChR (15)

CDK (14)

ERK (13)

HDAC (13)

PARP (13)

PPAR (13)

STAT (13)

FLT3 (12)

MEK (12)

Src (12)

HBV (11)

JAK (11)

PI3K (11)

Raf (10)

HCV (9)

PKC (9)

AMPK (8)

Btk (8)

CMV (8)

MMP (8)

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Compound Customization
  •  Specific Compounds
  •  Quantities
  •  Plate Map
  •  Concentration
  •  Form (Solid or Solution)
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    Product Name:
    FDA-Approved Anticancer Drug Library
    Cat. No.:
    HY-L122
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack
    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack

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