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FKK is an indazole derivative and also a novel bronchodilator.

For research use only. We do not sell to patients.

FKK Chemical Structure

FKK Chemical Structure

CAS No. : 78299-79-3

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FKK Related Antibodies

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Description

FKK is an indazole derivative and also a novel bronchodilator.

In Vivo

FKK is an indazole derivative and also a novel bronchodilator. FKK (0.1 to 3.0 mg/kg, i.v.) slightly increases respiratory frequency, left ventricular (LV) dp/dt max and myocardial contractile force. A slight increase followed by a decrease is observed in systemic blood pressure and LV systolic pressure. FKK causes direct vasodilation in the coronary, mesenteric and femoral vasculatures, but has no effect on the renal vasculature. It is particularly pertinent that FKK (30 mg/kg, i.d., enough to cause marked bronchodilation), unlike aminophylline (30 mg/kg, i.d.), does not significantly influence the cardiovascular system[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

329.23

Formula

C17H17BrN2
CAS No.
SMILES

CC1=CC2=C(C3=CC=CC=C3)N(CCC4)[N+]4=C2C=C1.[Br-]
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FKK78299-79-3OthersInhibitorinhibitorinhibit

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