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Famprofazone is a non-steroidal anti-inflammatory agent (NSAID) of the pyrazolone series, has analgesic, anti-inflammatory, and antipyretic effects.

For research use only. We do not sell to patients.

Famprofazone Chemical Structure

Famprofazone Chemical Structure

CAS No. : 22881-35-2

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500 mg USD 80 In-stock
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Famprofazone Related Antibodies

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Description

Famprofazone is a non-steroidal anti-inflammatory agent (NSAID) of the pyrazolone series, has analgesic, anti-inflammatory, and antipyretic effects.

Molecular Weight

377.52

Formula

C24H31N3O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1N(C2=CC=CC=C2)N(C)C(CN(C)C(C)CC3=CC=CC=C3)=C1C(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Ethanol : 25 mg/mL (66.22 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6489 mL 13.2443 mL 26.4887 mL
5 mM 0.5298 mL 2.6489 mL 5.2977 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% EtOH    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (6.62 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% EtOH    90% Corn Oil

    Solubility: ≥ 2.5 mg/mL (6.62 mM); Suspended solution

    This protocol yields a suspended solution of ≥ 2.5 mg/mL (saturation unknown). Suspended solution can be used for oral and intraperitoneal injection.

    Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 2.6489 mL 13.2443 mL 26.4887 mL 66.2217 mL
5 mM 0.5298 mL 2.6489 mL 5.2977 mL 13.2443 mL
10 mM 0.2649 mL 1.3244 mL 2.6489 mL 6.6222 mL
15 mM 0.1766 mL 0.8830 mL 1.7659 mL 4.4148 mL
20 mM 0.1324 mL 0.6622 mL 1.3244 mL 3.3111 mL
25 mM 0.1060 mL 0.5298 mL 1.0595 mL 2.6489 mL
30 mM 0.0883 mL 0.4415 mL 0.8830 mL 2.2074 mL
40 mM 0.0662 mL 0.3311 mL 0.6622 mL 1.6555 mL
50 mM 0.0530 mL 0.2649 mL 0.5298 mL 1.3244 mL
60 mM 0.0441 mL 0.2207 mL 0.4415 mL 1.1037 mL
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Famprofazone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Famprofazone22881-35-2OthersInhibitorinhibitorinhibit

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