Fulvestrant (R enantiomer)  (Synonyms: ICI 182780 (R enantiomer); ZD 9238 (R enantiomer); ZM 182780 (R enantiomer))

Fulvestrant R enantiomer (ICI 182780 R enantiomer) is the R enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC₅₀ of 9.4 nM.

606.77

C₃₂H₄₇F₅O₃S

1807900-80-6

C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])[C@H](CCCCCCCCC[S@](CCCC(F)(F)C(F)(F)F)=O)CC4=C(C=CC(O)=C4)[C@@]3([H])CC2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Caprioglio D, et al. An alternative synthesis of the breast cancer drug fulvestrant (Faslodex®): catalyst control over C-C bond formation. Chem Commun (Camb). 2015;51(80):14866-14868.  [Content Brief]

  [2]. Wakeling AE, et al. A potent specific pure antiestrogen with clinical potential. Cancer Res. 1991;51(15):3867-3873.  [Content Brief]