KFM19

Cat. No.: HY-U00251 Purity: 99.44%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

KFM19 is a potent, selective Adenosine receptor (A1-receptor) antagonist, with an IC₅₀ of 50 nM.

For research use only. We do not sell to patients.

KFM19 Chemical Structure

CAS No. : 133058-72-7

Size	Price	Stock	Quantity
Free Sample (0.1 - 0.5 mg)		Apply Now
5 mg	USD 165	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 240	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 450	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Adenosine A₁ receptor (A₁R) Adenosine A_2A receptor (A_2AR) Adenosine A_2B receptor (A_2BR) Adenosine A₃ receptor (A₃R)

Biological Activity
Purity & Documentation
References
Customer Review

Description

KFM19 is a potent, selective Adenosine receptor (A1-receptor) antagonist, with an IC₅₀ of 50 nM.

IC₅₀ & Target

IC50: 50 nM (Adenosine receptor)^[1]

Molecular Weight

318.37

Formula

C₁₆H₂₂N₄O₃

CAS No.

133058-72-7

Appearance

Solid

Color

Off-white to pink

SMILES

O=C(N1CCC)N(CCC)C2=C(N=C(C3CC(CC3)=O)N2)C1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (314.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.1410 mL	15.7050 mL	31.4100 mL
5 mM	0.6282 mL	3.1410 mL	6.2820 mL
10 mM	0.3141 mL	1.5705 mL	3.1410 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.44%

Select Batch:

Data Sheet (270 KB) SDS (251 KB)

COA (247 KB) HNMR (140 KB) RP-HPLC (164 KB) LCMS (181 KB)

Handling Instructions (2659 KB)

References

[1]. W.D. Bechtel, et al. KFM 19 antagonizes the adenosine-induced inhibition of electrically evoked acetylcholine release. Eur Neuropsychopharmacol. Sep. 1993, 3(3), Page 433

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.1410 mL	15.7050 mL	31.4100 mL	78.5250 mL
	5 mM	0.6282 mL	3.1410 mL	6.2820 mL	15.7050 mL
	10 mM	0.3141 mL	1.5705 mL	3.1410 mL	7.8525 mL
	15 mM	0.2094 mL	1.0470 mL	2.0940 mL	5.2350 mL
	20 mM	0.1570 mL	0.7852 mL	1.5705 mL	3.9262 mL
	25 mM	0.1256 mL	0.6282 mL	1.2564 mL	3.1410 mL
	30 mM	0.1047 mL	0.5235 mL	1.0470 mL	2.6175 mL
	40 mM	0.0785 mL	0.3926 mL	0.7852 mL	1.9631 mL
	50 mM	0.0628 mL	0.3141 mL	0.6282 mL	1.5705 mL
	60 mM	0.0523 mL	0.2617 mL	0.5235 mL	1.3087 mL
	80 mM	0.0393 mL	0.1963 mL	0.3926 mL	0.9816 mL
	100 mM	0.0314 mL	0.1570 mL	0.3141 mL	0.7852 mL

KFM19 Related Classifications

Neurological Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KFM19133058-72-7KFM 19KFM-19Adenosine ReceptorP1 receptorInhibitorinhibitorinhibit

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