1. Anti-infection
  2. HIV
  3. 9-Propenyladenine

9-Propenyladenine  (Synonyms: Mutagenic Impurity of Tenofovir Disoproxil; Tenofovir Impurity 2)

Cat. No.: HY-100079 Purity: 96.69%
SDS COA Handling Instructions

9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral agent known as nucleotide analogue reverse transcriptase inhibitors, which block reverse transcriptase, a crucial virus enzyme in HIV-1 and HBV.

For research use only. We do not sell to patients.

9-Propenyladenine Chemical Structure

9-Propenyladenine Chemical Structure

CAS No. : 1446486-33-4

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
USD 202 In-stock
Solution
10 mM * 1 mL in DMSO USD 202 In-stock
Solid
5 mg USD 310 In-stock
10 mg USD 500 In-stock
50 mg USD 1400 In-stock
100 mg USD 1960 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Other Forms of 9-Propenyladenine:

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Description

9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral agent known as nucleotide analogue reverse transcriptase inhibitors, which block reverse transcriptase, a crucial virus enzyme in HIV-1 and HBV.

IC50 & Target

HIV-1

 

Molecular Weight

175.19

Formula

C8H9N5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NC1=C2N=CN(/C=C/C)C2=NC=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : ≥ 29 mg/mL (165.53 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.7081 mL 28.5404 mL 57.0809 mL
5 mM 1.1416 mL 5.7081 mL 11.4162 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.7081 mL 28.5404 mL 57.0809 mL 142.7022 mL
5 mM 1.1416 mL 5.7081 mL 11.4162 mL 28.5404 mL
10 mM 0.5708 mL 2.8540 mL 5.7081 mL 14.2702 mL
15 mM 0.3805 mL 1.9027 mL 3.8054 mL 9.5135 mL
20 mM 0.2854 mL 1.4270 mL 2.8540 mL 7.1351 mL
25 mM 0.2283 mL 1.1416 mL 2.2832 mL 5.7081 mL
30 mM 0.1903 mL 0.9513 mL 1.9027 mL 4.7567 mL
40 mM 0.1427 mL 0.7135 mL 1.4270 mL 3.5676 mL
50 mM 0.1142 mL 0.5708 mL 1.1416 mL 2.8540 mL
60 mM 0.0951 mL 0.4757 mL 0.9513 mL 2.3784 mL
80 mM 0.0714 mL 0.3568 mL 0.7135 mL 1.7838 mL
100 mM 0.0571 mL 0.2854 mL 0.5708 mL 1.4270 mL
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9-Propenyladenine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
9-Propenyladenine
Cat. No.:
HY-100079
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