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NSC601980 shows antitumor activity in the yeast screening experiment, which can inhibit cell proliferation in the COLO 205 and HT29 with Log GI 50 of -6.

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NSC 601980 Chemical Structure

NSC 601980 Chemical Structure

CAS No. : 2070018-27-6

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10 mM * 1 mL in DMSO
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10 mM * 1 mL in DMSO USD 132 In-stock
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Based on 1 publication(s) in Google Scholar

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NSC 601980 Related Antibodies

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Description

NSC601980 shows antitumor activity in the yeast screening experiment, which can inhibit cell proliferation in the COLO 205 and HT29 with Log GI 50 of -6.6 and -6.9 respectively.

Molecular Weight

248.28

Formula

C15H12N4
CAS No.
Appearance

Solid

Color

Pink to red

SMILES

CC1=NC2=CC=CC=C2N=C1/N=N/C3=CC=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (100.69 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0277 mL 20.1386 mL 40.2771 mL
5 mM 0.8055 mL 4.0277 mL 8.0554 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C1

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.0277 mL 20.1386 mL 40.2771 mL 100.6928 mL
5 mM 0.8055 mL 4.0277 mL 8.0554 mL 20.1386 mL
10 mM 0.4028 mL 2.0139 mL 4.0277 mL 10.0693 mL
15 mM 0.2685 mL 1.3426 mL 2.6851 mL 6.7129 mL
20 mM 0.2014 mL 1.0069 mL 2.0139 mL 5.0346 mL
25 mM 0.1611 mL 0.8055 mL 1.6111 mL 4.0277 mL
30 mM 0.1343 mL 0.6713 mL 1.3426 mL 3.3564 mL
40 mM 0.1007 mL 0.5035 mL 1.0069 mL 2.5173 mL
50 mM 0.0806 mL 0.4028 mL 0.8055 mL 2.0139 mL
60 mM 0.0671 mL 0.3356 mL 0.6713 mL 1.6782 mL
80 mM 0.0503 mL 0.2517 mL 0.5035 mL 1.2587 mL
100 mM 0.0403 mL 0.2014 mL 0.4028 mL 1.0069 mL
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NSC 601980 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NSC 6019802070018-27-6NSC601980NSC-601980OthersInhibitorinhibitorinhibit

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