2. Natural Products
  3. Plants
  4. Leguminosae
  5. Erythrina latissima E. Mey.

Erythrina latissima E. Mey.

Erythrina latissima E. Mey. (6):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N1902
    4-Hydroxyphenylacetic acid 156-38-7 99.95%
    4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2.
    4-Hydroxyphenylacetic acid
  • HY-P1680
    Astin C 148057-23-2 98.77%
    Astin C (Asterin) is a cyclic pentapeptide with anticancer and anti-inflammatory properties.
    Astin C
  • HY-N1931
    Epifriedelanol 16844-71-6 ≥98.0%
    Epifriedelanol is a triterpenoid isolated from the root bark of Ulmus davidiana, with antitumor activity. Epifriedelanol inhibits cellular senescence in human primary cells.
    Epifriedelanol
  • HY-P3145
    Astin A 151201-75-1 98.06%
    Astin A is an antitumor cyclic pentapeptide. Astin A can be isolated from Aster tataricus.
    Astin A
  • HY-P3148
    Astin B 151201-76-2
    Astin B is a orally active and potent cyclic pentapeptide, that can be isolated from Aster tataricus. Astin B has hepatotoxic effects in vitro and in vivo and that hepatic injury was primarily mediated by apoptosis in a mitochondria/caspase-dependent manner. Astin B induces autophagy in L-02 cells, increases LC3-II and decreases p62 expression.
    Astin B
  • HY-N1902R
    4-Hydroxyphenylacetic acid (Standard) 156-38-7
    4-Hydroxyphenylacetic acid (Standard) is the analytical standard of 4-Hydroxyphenylacetic acid. This product is intended for research and analytical applications. 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2. IC50 & Target:Nrf2 In Vivo: 4-Hydroxyphenylacetic acid (6, 12, or 25 mg/kg) increases Nrf2 translocation to the nucleus and enhances the activity of phase II and antioxidant enzymes. The protein levels of nuclear Nrf2 are increased by 170% and 230% in pre-treated 12 and 25 mg/kg 4-Hydroxyphenylacetic acid groups, respectively, compared with the control group.The 4-Hydroxyphenylacetic acid pretreatment at a final dose of 25 mg/kg markedly and selectively up-regulated the target genes of phase II enzymes and resulted in higher up-regulation than that of the control group by 270%, 400%, and 500% or UGT1A1, UGT1A9, and SULT2A1, respectively. 4-Hydroxyphenylacetic acid also suppresses the expression of CYP2E1.
    4-Hydroxyphenylacetic acid (Standard)