2. Natural Products
  3. Plants
  4. Meliaceae
  5. Azadirachta indica A. Juss.

Azadirachta indica A. Juss.

Azadirachta indica A. Juss. (11):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-116035
    Nimbolide 25990-37-8 99.72%
    Nimbolide is a triterpene compound that can be isolated from neem (Azadirachta indica), possesses anticancer and antiproliferative activity. Nimbolide induces tumor cell apoptosis by inhibiting NF-κB and CDK4/CDK6 kinase. Nimbolide suppresses the Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways.
    Nimbolide
  • HY-126741
    Azadirachtin 11141-17-6 99.06%
    Azadirachtin is an oral active triterpenoid compound with anticancer, antimalarial, anti-inflammatory, and insecticidal activities. Azadirachtin induces cell apoptosis through the mitochondrial pathway (by inhibiting Bcl-2/Bax ratio or activating Apaf-1 and caspase-3) or through death receptors (by inhibiting TNFR activation). Additionally, Azadirachtin exerts its anti-inflammatory effects by inhibiting NF-кB signaling pathway activation, and it exhibits insecticidal activity by inducing apoptosis in insect cells.
    Azadirachtin
  • HY-N10437
    6-Acetylnimbandiol 1281766-66-2
    6-Acetylnimbandiol (6-O-Acetylnimbandiol) is a non-cytotoxic tyrosinase inhibitor (IC50=69.85 μM) that effectively inhibits melanin production and MITF expression. 6-Acetylnimbandiol can be used in melanoma research.
    6-Acetylnimbandiol
  • HY-N1654
    2',3'-Dehydrosalannol 97411-50-2
    2',3'-Dehydrosalannol is a potent antibacterial agent. 2',3'-Dehydrosalannol shows antibacterial activity against K. pneumonia ATCC 13883, P. aeruginosa ATCC 27853, S. aureus ATCC 25922, E. coli ATCC 11775, and E. faecalis ATCC 10541, with MIC values of 0.78, 1.56, 1.56, 6.25, and 25 µg/mL, respectively.
    2',3'-Dehydrosalannol
  • HY-N3694
    Deacetylnimbin 18609-16-0
    Deacetylnimbin is a limonoid isolated from Azadirachta indica. Deacetylnimbin can be used as a plant metabolite, a food repellent and as a growth regulator for insects such as S. litura, P. ricini and O. fscovittata.
    Deacetylnimbin
  • HY-126741R
    Azadirachtin (Standard) 11141-17-6
    Azadirachtin (Standard) is the analytical standard of Azadirachtin. This product is intended for research and analytical applications. Azadirachtin, one of the most promising botanical insecticides, is widely used for pest control. Azadirachtin induces apoptosis in insect cell lines, including Sf9, SL-1 and BTI-Tn-5B1-4.
    Azadirachtin (Standard)
  • HY-N10507
    Methyl 14-methylpentadecanoate 5129-60-2
    Methyl 14-methylpentadecanoate is an ester product.
    Methyl 14-methylpentadecanoate
  • HY-163450
    Nimbiol 561-95-5
    Nimbiol exhibits binding energy for FtsZ and shows potential anti-FtsZ effect.
    Nimbiol
  • HY-N1710
    28-Deoxonimbolide 126005-94-5
    28-Deoxonimbolide is a nimbin (HY-N3187) type limonoid, that can be isolated from Azadirachta indica seed extracts. 28-Deoxonimbolide shows anticancer activity. 28-Deoxonimbolide induces apoptotic cell death in HL60 cells via both the mitochondrial- and the death receptor-mediated pathways.
    28-Deoxonimbolide
  • HY-121731
    Nimbocinone 105532-11-4
    Nimbocinone, isolated from Azadirachta indica, exhibits antidiabetogenic activity.
    Nimbocinone
  • HY-N3695
    6-Deacetylnimbinene 912545-53-0
    6-Deacetylnimbinene is a triterpenoid product that can be isolated from Azadirachta indica A. Juss.
    6-Deacetylnimbinene