2. Natural Products
  3. Plants
  4. Simaroubaceae
  5. Brucea javanica (L.) Merr.

Brucea javanica (L.) Merr.

Brucea javanica (L.) Merr. (33):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-19543
    Brusatol 14907-98-3 99.89%
    Brusatol (NSC?172924) is a unique inhibitor of the Nrf2 pathway that sensitizes a broad spectrum of cancer cells to Cisplatin and other chemotherapeutic agents. Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism. Brusatol can be developed into an adjuvant chemotherapeutic agent. Brusatol increases cellular apoptosis.
    Brusatol
  • HY-N3014
    Bruceine D 21499-66-1 99.53%
    Bruceine D is a Notch inhibitor with anti-cancer activity and induces apoptosis in several human cancer cells. Bruceine D is an effective botanical insect antifeedant with outstanding systemic properties, causing potent pest growth inhibitory activity. Bruceine D has strong anthelmintic activity against D. intermedius with an EC50 value of 0.57 mg/L.
    Bruceine D
  • HY-N0840
    Bruceantin 41451-75-6 99.94%
    Bruceantin(NSC165563) is first isolated from Brucea javanica, a tree used in Ethiopia for the treatment of cancer, and activity was observed against B16 melanoma, colon 38, and L1210 and P388 leukemia in mice.
    Bruceantin
  • HY-N0841
    Bruceine A 25514-31-2 98.01%
    Bruceine A(NSC310616; Dihydrobrusatol) is a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.
    Bruceine A
  • HY-111806
    3,7,4'-Trihydroxyflavone 2034-65-3 99.44%
    3,7,4'-Trihydroxyflavone, isolated from Rhus javanica var. roxburghiana, is a flavonoid with DNA strand-scission activity.
    3,7,4'-Trihydroxyflavone
  • HY-N8146
    Bruceantinol 53729-52-5 98.89%
    Bruceantinol, a quassinoid isolated from Brucea javanica, inhibits pepper mottle virus in pepper. Bruceantinol is a STAT3 inhibitor demonstrating potent antitumor activity in in vitro and in vivo human colorectal cancer (CRC) models. Bruceantinol strongly inhibits STAT3 DNA-binding ability (IC50=2.4 pM), blocks the constitutive and IL-6-induced STAT3 activation, and suppresses transcription of MCL-1, PTTG1, survivin and c-Myc.
    Bruceantinol
  • HY-N4210
    Yadanziolide A 95258-14-3 99.42%
    Yadanziolide A, isolated from the cultivated dry seeds of Brucea javanica, has strong antiviral activities with IC50 of 5.5 μM against tobacco mosaic virus. Yadanziolide A shows significant antitumor effects.
    Yadanziolide A
  • HY-N3013
    Bruceine B 25514-29-8 99.60%
    Bruceine B inhibits protein synthesis and nucleic acid synthesis.
    Bruceine B
  • HY-N4257
    Yadanzioside A 95258-15-4 ≥98.0%
    Yadanziolide A, a quassinoid glycoside from Brucea javanica, has antitumor activity.
    Yadanzioside A
  • HY-N7190
    Yadanzioside F 95258-11-0 ≥98.0%
    Yadanzioside F is one of the toxic components found in Brucea javanica. Brucea javanica has demonstrated a variety of antitumoral, antimalarial, and anti-inflammatory properties.
    Yadanzioside F
  • HY-N7532
    Yadanzioside I 99132-95-3
    Yadanzioside I is a potent anti-tobacco mosaic virus (TMV) quassinoid with an IC50 of 4.22 μM.
    Yadanzioside I
  • HY-N3015
    Bruceine E 21586-90-3
    Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect. Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ (HY-13753))-induced diabetic rats at lower dose.
    Bruceine E
  • HY-141508
    Flazin 100041-05-2
    Flazin is a non-enzymatic protein glycation inhibitor, also inhibits peroxynitrite (ONOO-), with an IC50 value of 85.31 μM for bovine serum albumin (BSA) glycation and an EC50 value of 71.99 μM for ONOO-. Flazin can be used for researching diabetes and neuronal disorders. Flazin also can used as a lipid droplet (LD) regulator against lipid disorders, and a xanthine oxidase (XOD) inhibitor.
    Flazin
  • HY-125067
    Yadanzioside P 79439-84-2
    Yadanzioside P is an antileukemic quassinoid glycoside. Yadanzioside P can be isolated from the seeds of Brucea javanica (L.). Yadanzioside P can be used for the research of cancer.
    Yadanzioside P
  • HY-133096
    Yadanzioside K 101559-98-2
    Yadanzioside K is a natural quassinoid glucoside found in Brucea amarissima.
    Yadanzioside K
  • HY-133097
    Yadanzioside M 101559-99-3
    Yadanzioside M is a natural compound with anti-cancer activity.
    Yadanzioside M
  • HY-135421
    Dehydrobruceantinol 99132-99-7
    Dehydrobruceantinol is a natural product that can be isolated from Brucea javanica.
    Dehydrobruceantinol
  • HY-N10591
    Bruceantarin 41451-76-7
    Bruceantarin is a potent antineoplastic agent. Bruceantarin can be used for leukemia and breast cancer research.
    Bruceantarin
  • HY-N10897
    Bruceantinol A 948038-36-6
    Bruceantinol A, a natural compound, can be isolated from Brucea javanica seeds.
    Bruceantinol A
  • HY-N10899
    Bruceine J 948038-38-8
    Bruceine J, a quassinoid, is a nature product that could be isolated from fruits of Br. jaVanica. Bruceine J has anti-Babesial activity.
    Bruceine J