2. Natural Products
  3. Plants
  4. Moraceae
  5. Humulus lupulus L.

Humulus lupulus L.

Synonyms: hops

Humulus lupulus L. (24):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N1067
    Xanthohumol 6754-58-1 99.97%
    Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV).
    Xanthohumol
  • HY-N6084
    Humulone 26472-41-3 99.46%
    Humulone (α-Lupulic acid), a prenylated phloroglucinol derivative, is a potent cyclooxygenase-2 (COX-2) inhibitor. Humulone acts as a positive modulator of GABAA receptor at low micromolar concentrations. Humulone is an inhibitor of bone resorption. Humulone possesses antioxidant, anti-angiogenic and apoptosis-inducing properties.
    Humulone
  • HY-N2584A
    Isoxanthohumol 521-48-2 99.91%
    Isoxanthohumol is a prenylflavonoid from hops and beer. Isoxanthohumol exhibits an antiproliferative activity against several human cancer cell lines. Isoxanthohumol inhibits the development of lung metastatic foci in tumor-challenged animals. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV).
    Isoxanthohumol
  • HY-N1066
    Xanthohumol D 274675-25-1 99.21%
    Xanthohumol D, isolated from hops, is an inhibitor of quinone reductase-2 (QR-2) with the IC50 value of 110 μM, and binds to the active site of QR-2. Xanthohumol D shows antiproliferative activity on human cancer cell lines in vitro.
    Xanthohumol D
  • HY-107198
    (2S)-6-Prenylnaringenin 68236-13-5 99.43%
    (2S)-6-Prenylnaringenin is the most efficient compound in forebrain. (2S)-6-Prenylnaringenin acts as a GABAA positive allosteric modulator at α+β- binding interface.
    (2S)-6-Prenylnaringenin
  • HY-N1067R
    Xanthohumol (Standard) 6754-58-1
    Xanthohumol (Standard) is the analytical standard of Xanthohumol. This product is intended for research and analytical applications. Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV).
    Xanthohumol (Standard)
  • HY-N2584AR
    Isoxanthohumol (Standard) 521-48-2
    Isoxanthohumol (Standard) is the analytical standard of Isoxanthohumol. This product is intended for research and analytical applications. Isoxanthohumol is a prenylflavonoid from hops and beer. Isoxanthohumol exhibits an antiproliferative activity against several human cancer cell lines. Isoxanthohumol inhibits the development of lung metastatic foci in tumor-challenged animals. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV).
    Isoxanthohumol (Standard)
  • HY-124923R
    Lupulone (Standard) 468-28-0
    Lupulone (Standard) is the analytical standard of Lupulone. This product is intended for research and analytical applications. Lupulone is a beta-acid from the hop plant H. lupulus with diverse biological activities including antibacterial, antioxidant, and anticarcinogenic properties.
    Lupulone (Standard)
  • HY-122966
    Desmethylxanthohumol 115063-39-3 99.66%
    Desmethylxanthohumol is a prenylated hydroxychalcone isolated from hop cones (Humulus lupulus L.). Desmethylxanthohumol is a powerful apoptosis inducing agent. Desmethylxanthohumol has antiplasmodial, antiproliferative, and antioxidant bioactivities.
    Desmethylxanthohumol
  • HY-N2584
    (2S)-Isoxanthohumol 70872-29-6 99.42%
    (2S)-Isoxanthohumol is a microbial biotransformed metabolite of the hop prenylflavanone Isoxanthohumol.
    (2S)-Isoxanthohumol
  • HY-N2787
    8-​Prenylnaringenin 53846-50-7 99.34%
    8-prenylnaringenin is a prenylflavonoid isolated from hop cones Humulus lupulus, with cytotoxicity. 8-prenylnaringenin has anti-proliferative activity against HCT-116 colon cancer cells via induction of intrinsic and extrinsic pathway-mediated apoptosis. 8-Prenylnaringenin also promotes recovery from immobilization-induced disuse muscle atrophy through activation of the Akt phosphorylation pathway in mice .
    8-​Prenylnaringenin
  • HY-N11769
    Xanthohumol C 189299-05-6 99.80%
    Xanthohumol C is a prenylchalcone, that can be isolated from the hops of Humulus lupulus.
    Xanthohumol C
  • HY-124923
    Lupulone 468-28-0 ≥99.0%
    Lupulone is a beta-acid from the hop plant H. lupulus with diverse biological activities including antibacterial, antioxidant, and anticarcinogenic properties.
    Lupulone
  • HY-122375
    Palustrol 5986-49-2
    Palustrol is a natural sesquiterpenoid compound.
    Palustrol
  • HY-122416
    6,8-Diprenylnaringenin 68236-11-3
    6,8-Diprenylnaringenin (Lonchocarpol A; Senegalensin), a hop prenylflavonoid, is a inhibitor of breast cancer resistance protein (BCRP/ABCG2). 6,8-Diprenylnaringenin inhibits ABCG2-mediated efflux of Mitoxantrone, and 3H-Methotrexate transport (IC50=0.41 μM) in HEK293 cells. 6,8-Diprenylnaringenin exhibits some estrogenicity, but its potency is less than 1% of that of 8-Prenylnaringenin.
    6,8-Diprenylnaringenin
  • HY-N10668
    2-(3-Hydroxy-2-oxoindolin-3-yl)-acetic acid 57061-17-3
    2-(3-Hydroxy-2-oxoindolin-3-yl)-acetic acid (compound 29) is a natural polyphenol compound found in hop bract.
    2-(3-Hydroxy-2-oxoindolin-3-yl)-acetic acid
  • HY-N1067A
    (E/Z)-Xanthohumol 569-83-5
    (E/Z)-Xanthohumol is a flavonoid isolated from hopfen.
    (E/Z)-Xanthohumol
  • HY-N10867
    β-Acids colupulone 468-27-9
    β-Acids colupulone is the bitter substance. β-Acids colupulone can be isolated from hops.
    β-Acids colupulone
  • HY-N10917
    Xanthohumol I 688360-06-7
    Xanthohumol I, a chalkone, is a derivative of Xanthohumol (HY-N1067). Xanthohumol is a Cholinesterase (ChE) inhibitor, which inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) wih IC50s of 71.34 μM and 32.67 μM, respectively. The hydroxy compound of Xanthohumol (3-hydroxy-xanthohumol), also shoes inhibitory effect on AChE and BChE with IC50s of 51.25 μM and 63.07 μM.
    Xanthohumol I
  • HY-N11055
    7-O-Methyl-6-Prenylnaringenin 261776-61-8
    7-O-Methyl-6-Prenylnaringenin is an active compound. 7-O-Methyl-6-Prenylnaringenin can be isolated from Humulus lupulus.
    7-O-Methyl-6-Prenylnaringenin