2. Peptides
  3. Peptide and Derivatives
  4. Therapeutic Peptides
  5. Ornipressin

Ornipressin is a potent vasoconstrictor, hemostatic and renal agent.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Ornipressin Chemical Structure

Ornipressin Chemical Structure

CAS No. : 3397-23-7

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5 mg USD 50 In-stock
10 mg USD 80 In-stock
25 mg USD 150 In-stock
50 mg USD 240 In-stock
100 mg USD 360 In-stock
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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Ornipressin:

Ornipressin Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Ornipressin is a potent vasoconstrictor, hemostatic and renal agent.

Cellular Effect
Cell Line Type Value Description References
CHO-K1 EC50
71 nM
Compound: 3, OVP
Agonist activity at human OT receptor expressed in CHO-K1 cells by luciferase reporter gene assay
Agonist activity at human OT receptor expressed in CHO-K1 cells by luciferase reporter gene assay
[PMID: 21688787]
Flp-In-293 EC50
7.5 nM
Compound: 3, OVP
Agonist activity at recombinant human vasopressin V1b receptor expressed in Flp-In-293 cells by luciferase reporter gene assay
Agonist activity at recombinant human vasopressin V1b receptor expressed in Flp-In-293 cells by luciferase reporter gene assay
[PMID: 21688787]
HEK293 EC50
0.35 nM
Compound: 3, OVP
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay
[PMID: 21688787]
HEK293 EC50
0.45 nM
Compound: 3, OVP
Agonist activity at recombinant human vasopressin V2 receptor expressed in HEK293 cells by luciferase reporter gene assay
Agonist activity at recombinant human vasopressin V2 receptor expressed in HEK293 cells by luciferase reporter gene assay
[PMID: 21688787]
HEK293 EC50
0.69 nM
Compound: 3, OVP
Agonist activity at recombinant human vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay
Agonist activity at recombinant human vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay
[PMID: 21688787]
Molecular Weight

1042.19

Formula

C45H63N13O12S2
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Cys-Tyr-Phe-Gln-Asn-Cys-Pro-{Orn}-Gly-NH2 (Disulfide bridge: Cys1-Cys6)
Sequence Shortening

CYFQNCP-{Orn}-G-NH2 (Disulfide bridge: Cys1-Cys6)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 75 mg/mL (71.96 mM; Need ultrasonic)

DMSO : 22.22 mg/mL (21.32 mM; ultrasonic and adjust pH to 3 with 1 M HCL; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9595 mL 4.7976 mL 9.5952 mL
5 mM 0.1919 mL 0.9595 mL 1.9190 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 50 mg/mL (47.98 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 0.9595 mL 4.7976 mL 9.5952 mL 23.9879 mL
5 mM 0.1919 mL 0.9595 mL 1.9190 mL 4.7976 mL
10 mM 0.0960 mL 0.4798 mL 0.9595 mL 2.3988 mL
15 mM 0.0640 mL 0.3198 mL 0.6397 mL 1.5992 mL
20 mM 0.0480 mL 0.2399 mL 0.4798 mL 1.1994 mL
H2O 25 mM 0.0384 mL 0.1919 mL 0.3838 mL 0.9595 mL
30 mM 0.0320 mL 0.1599 mL 0.3198 mL 0.7996 mL
40 mM 0.0240 mL 0.1199 mL 0.2399 mL 0.5997 mL
50 mM 0.0192 mL 0.0960 mL 0.1919 mL 0.4798 mL
60 mM 0.0160 mL 0.0800 mL 0.1599 mL 0.3998 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Ornipressin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ornipressin3397-23-7POR-8POR8POR 8OthersInhibitorinhibitorinhibit

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