1. GPCR/G Protein Neuronal Signaling
  2. Adrenergic Receptor
  3. Pamatolol

Pamatolol is a cardioselective beta-adrenoceptor antagonist without sympathomimetic activity.

For research use only. We do not sell to patients.

Pamatolol Chemical Structure

Pamatolol Chemical Structure

CAS No. : 59110-35-9

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Description

Pamatolol is a cardioselective beta-adrenoceptor antagonist without sympathomimetic activity.

In Vivo

Pamatolol is well absorbed in the gastro-intestinal tract and excreted in the urine of man, dogs, rats and mice after oral administration, mainly in unchanged form, within 24 hrs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

310.39

Formula

C16H26N2O4

CAS No.
SMILES

O=C(OC)NCCC1=CC=C(OCC(O)CNC(C)C)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
Animal Administration
[1]

Three male Sprague-Dawley rats weighing 200-250 g are given pamatolol-sulphate dissolved in water at a dose of 50 mg/kg (10 μCi/mg) by means of a stomach tube. The rats are housed in metabolic cages that allows for separate collection of urine and feces for a 24 hr period. They are given a commercial pellet diet and drinking water ad libitum.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Pamatolol
Cat. No.:
HY-U00019
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