2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N6773
    Cytochalasin A 14110-64-6 99.61%
    Cytochalasin A is a cell-permeable fungal toxin that is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC50=3 μM) and inhibits actin polymerization and interferes with microtubule assembly by reacting with sulfhydryl groups. Antibiotic and fungicidal activitives.
    Cytochalasin A
  • HY-N6781
    Ophiobolin A 4611-05-6 99.53%
    Ophiobolin A, a fungal metabolite and a phytotoxin, is a potent and irreversibly inhibitor of calmodulin-activated cyclic nucleotide phosphodiesterase, with an IC50 value of 9 μM. Ophiobolin A antimicrobial and anticancer activity.
    Ophiobolin A
  • HY-N7082
    D-​Arabinose 28697-53-2 ≥98.0%
    D-Arabinose, a monosaccharide, shows strong growth inhibition against the Caenorhabditis elegans with an IC50 of 7.5 mM.
    D-​Arabinose
  • HY-N7121
    Erythromycin estolate 3521-62-8 ≥98.0%
    Erythromycin estolate, erythromycin derivative, is a macrolide antibiotic used in the treatment of a wide variety of bacterial infections. Erythromycin estolate causes several cases of liver injury which mostly include cholestatic hepatitis. Erythromycin estolate toxicity is related to its inhibitory effect on bile acid transport.
    Erythromycin estolate
  • HY-N7141
    Spiramycin I 24916-50-5
    Spiramycin I is a macrolide antibiotic and antiparasitic.
    Spiramycin I
  • HY-N8015
    Octanal 124-13-0 99.57%
    Octanal is a fragrant aldehyde with antioxidant and antibacterial activity. Its antifungal effect against G. citri-aurantii may be related to the disruption of cell membrane integrity and the leakage of cellular components. Additionally, Octanal exhibits cytotoxicity towards HeLa cells, with an IC50 value of 3.5 μg/mL.
    Octanal
  • HY-N9388
    Andrograpanin 82209-74-3 99.89%
    Andrograpanin, a bioactive compound from Andrographis paniculata, exhibits anti-inflammatory and anti-infectious properties.
    Andrograpanin
  • HY-P1350
    H-Lys-Trp-Lys-OH 38579-27-0 99.97%
    H-Lys-Trp-Lys-OH is a small molecule peptide which displays antibacterial and antiviral activities extracted from patent CN 104072579 A, Compound AMP12.
    H-Lys-Trp-Lys-OH
  • HY-P2695
    STh 118447-40-8 99.06%
    STh, an Escherichia coli heat-stable toxin, is a 19 amino acid polypeptide encompassing three disulfide bridges. STh is an antigen of interest in the search for a broad coverage enterotoxigenic Escherichia coli (ETEC) vaccine.
    STh
  • HY-P3512
    Iseganan 257277-05-7
    Iseganan is an anti-microbial peptide that is active against both Gram-positive and Gram-negative bacteria and fungi. Iseganan kills a broad-spectrum of bacteria and fungi by attaching to and destroying the integrity of the lipid cell membranes. Iseganan can be used for oral mucositis research.
    Iseganan
  • HY-P4086
    Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) 1678417-57-6 98.00%
    Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R), a chimeric peptide consisting of 29 amino acids, is synthesized by adding nona-arginine motif to the carboxy terminus of RVG (rabies virus glycoprotein). Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) is positively charged and able to bind negatively charged nucleic acids via charge interaction.
    Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R)
  • HY-100725
    BM212 146204-42-4 99.51%
    BM212 is a potent Mycobacterial membrane protein Large 3 (MmpL3) inhibitor. BM212 has strong bactericidal activity against both M. tuberculosis and some nontuberculosis mycobacteria. BM212 exhibits antimycobacterial activity against M. tuberculosis H37Rv with an MIC of 5 µM.
    BM212
  • HY-103249
    Reutericyclin 303957-69-9 98.11%
    Reutericyclin (Reutericycline), a unique tetramic acid, is an antibiotic produced by some strains of Lactobacillus reuteri. Reutericyclin (Reutericycline) exhibits a broad inhibitory spectrum including Lactobacillus spp., Bacillus subtilis, B. cereus, Enterococcus faecalis, Staphylococcus aureus, and Listeria innocua.
    Reutericyclin
  • HY-106282
    BIT-225 917909-71-8 98.87%
    BIT-225 is an inhibitor for Vpu protein through block of Vpu ion channel, and thus inhibits the release of HIV-1, especially in monocyte-derived macrophages (EC50 is 2.25 μM), without significant cytotoxicity (TC50 is 284 μM).
    BIT-225
  • HY-106302
    Duramycin 1391-36-2 99.46%
    Duramycin (Moli1901) is a lantibiotic derived from Streptomyces cinnamoneuma. Duramycin also is a antimicrobial peptide. Duramycin can be used for the research of cystic fibrosis (CF).
    Duramycin
  • HY-106755
    Tucaresol 84290-27-7 98.95%
    Tucaresol is an orally bioavailable immunopotentiatory drug that show to enhance T-helper-cell activity, with the induction of increased IL-2 and IFN-γ levels in mice and humans. Tucaresol has anti-HIV effect.
    Tucaresol
  • HY-107496
    Imidocarb dipropionate 55750-06-6 99.07%
    Imidocarb dipropionate is a potent antiprotozoal agent. Imidocarb dipropionate is active against the parasite B. bovis with an IC50 of 87 μg/mL.
    Imidocarb dipropionate
  • HY-107814
    Nicarbazin 330-95-0 ≥98.0%
    Nicarbazin is an effective anticoccidial agent for chickens.
    Nicarbazin
  • HY-107902
    RIG-1 modulator 1 1428729-63-8 99.54%
    RIG-1 modulator 1 is an anti-viral compound which can be useful for the treatment of viral infections including influenza virus, HBV, HCV and HIV extracted from patent WO 2015172099 A1.
    RIG-1 modulator 1
  • HY-108700
    N-3-Oxo-octanoyl-L-homoserine lactone 147795-39-9 98.05%
    N-3-Oxo-octanoyl-L-homoserine lactone, a quorum-sensing signal, is an Agrobacterium autoinducer.
    N-3-Oxo-octanoyl-L-homoserine lactone
Cat. No. Product Name / Synonyms Application Reactivity