SZ1676

Cat. No.: HY-U00162: FAQs
Data Sheet Handling Instructions

Molarity Calculator

SZ1676 is a derivative of SZ1677, which is a neuromuscular blocking agent.

For research use only. We do not sell to patients.

SZ1676 Chemical Structure

CAS No. : 159325-23-2

Size		Stock
MOQ		Minimum order quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote
Other size		Get quote

Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Protocol
Purity & Documentation
References
Customer Review

Description	SZ1676 is a derivative of SZ1677, which is a neuromuscular blocking agent.
In Vivo	SZ1676 is the 3-acetoxy derivative^[1]. The neuromuscular (NM) effects of SZ1676 and SZ1677 are compared in beagle dogs. SZ1677 (ED₉₀=19.2±2.6 μg/kg) is 1.86 times more potent than SZ1676 (ED₉₀=35.8±2.5 μg/kg)^[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight	707.78
Formula	C₃₇H₅₉BrN₂O₆
CAS No.	159325-23-2
SMILES	C[C@@]12[C@](C[C@H]([N+]3(CCCC3)CC=C)[C@@H]2OC(C)=O)([H])[C@@]4([H])[C@]([C@@]5([C@@](C[C@H](OC(C)=O)[C@@H](N6CCC7(OCCO7)CC6)C5)([H])CC4)C)([H])CC1.[Br-]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (273 KB) Handling Instructions (2659 KB)
References	[1]. B?azewicz A, et al. Application of high-performance liquid chromatography with amperometric and coulometric detection to the analysis of SZ1677, a new neuromuscular blocking agent, and its two derivatives. J Chromatogr A. 2008 Sep 12;1204(1):114-8. [Content Brief] [2]. Francis F. Foldes, et al. Comparison of the Neuromuscular Effects of SZ1676, SZ1677 and Vecuronium in Beagle Dogs. Muscle Relaxants pp 379-379.

Animal Administration
^[2]

Dogs^[2]
Beagle dogs of about 10 kg body weight, anesthetized with isofurane are intubated and mechanically ventilated with O₂, One fore-leg is fixed above the elbow and the wrist and the ulnar nerve is stimulated at the elbow, percutaneously,with supramaximal electrical impulses of 0.2 ms duration at 0.1 or 0.4 Hz.The force of flxion of the paw (P) is quantitated and contiuously recorded, At first the ED₅₀, ED₉₀ and ED₉₅ of the 2 muscle relaxants (MR) are determined.Thirty min after maximal spontaneous recovery of P,the calculated 2×ED₉₀ is injected and the time course ol the NM and circulatory effects are determined.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References

[1]. B?azewicz A, et al. Application of high-performance liquid chromatography with amperometric and coulometric detection to the analysis of SZ1677, a new neuromuscular blocking agent, and its two derivatives. J Chromatogr A. 2008 Sep 12;1204(1):114-8. [Content Brief]

[2]. Francis F. Foldes, et al. Comparison of the Neuromuscular Effects of SZ1676, SZ1677 and Vecuronium in Beagle Dogs. Muscle Relaxants pp 379-379.

SZ1676 Related Classifications

Neurological Disease

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SZ1676159325-23-2SZ 1676SZ-1676OthersInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks

Product Name

Lot #

Applicant Name *

Email Address *

Phone Number

Department *

Organization Name *

Country or Region *

Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

SZ1676

SZ1676 Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

Protocol

Purity & Documentation

References

Customer Review