2. Signaling Pathways
  3. Neuronal Signaling
    Stem Cell/Wnt
  4. γ-secretase
  5. γ-secretase Control

γ-secretase Control

γ-secretase Controls (2):

Cat. No. Product Name Effect Purity
  • HY-100604A
    (R)-JNJ-40418677
    		Control 99.27%
    (R)-JNJ-40418677 is the R-enantiomer of JNJ-40418677 (HY-100604).
  • HY-14176A
    (1R,3S)-Compound E
    		Control 99.82%
    (1R,3S)-Compound E is the isomer of Compound E (HY-14176), and can be used as an experimental control. Compound E is a γ-secretase inhibitor. Compound E bloks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively.