2. Signaling Pathways
  3. GPCR/G Protein
  4. Adenosine Receptor
  5. Adenosine A3 receptor (A3R) Isoform
  6. Adenosine A3 receptor (A3R) Agonist

Adenosine A3 receptor (A3R) Agonist

Adenosine A3 receptor (A3R) Agonists (8):

Cat. No. Product Name Effect Purity
  • HY-19365
    AB-MECA
    		Agonist 98.32%
    AB-MECA is a high affinity A3 adenosine receptor agonist with a binding Ki of 430.5 nM for human A3 receptors in CHO cells. AB-MECA can enhance plasma histamine level.
  • HY-123203
    CP-608039
    		Agonist
    CP-608039 is a potent and selective adenosine A3 receptor agonist. CP-608039 can be used for ischemic myocardial injury research.
  • HY-158180
    A3AR agonist 4
    		Agonist
    A3AR agonist 4 is an A3 adenosine receptor (A3AR) agonist (Ki: 1.24 nM for hA3AR). A3AR agonist 4 inhibits cAMP production with an EC50 of 0.17 nM. A3AR agonist 4 can be used for research of inflammation and pain.
  • HY-139694
    hA3AR agonist 1
    		Agonist
    hA3AR agonist 1 is a potent human A3 adenosine receptor (hA3AR) agonist with a Ki value of 2.40 nM.
  • HY-151899
    A3AR modulator 1
    		Agonist
    A3AR modulator 1 (MRS8054) is an orally active A3 adenosine receptor (A3AR) (Adenosine Receptor) positive allosteric modulator (PAM). A3AR modulator 1 greatly enhances Cl-IB-MECA-stimulated [35S]GTPγS binding Emax.
  • HY-110202
    MRS5698
    		Agonist
    MRS5698 is a selective Gi protein-coupled A3 adenosine receptor (A3AR) agonist, with Kis of approximately 3 nM for human and mouse A3AR, respectively. MRS5698 can be used for the research of pain and psoriasis.
  • HY-W777125
    2-Chloro-3-deazaadenosine
    		Agonist
    2-Chloro-3-deazaadenosine is agonists for adenosine receptor, with Kis of 0.3, 0.08, 25.5 and 1.9 μM, for A1, A2A, A2B, and A3 receptors, respectively.
  • HY-162851
    Adenosine receptor agonist 1
    		Agonist
    Adenosine receptor agonist 1 (compound 6m) is an A3 adenosine receptor (AR) partial agonist with Ki value of 6.7 nM.