2. Signaling Pathways
  3. Immunology/Inflammation
  4. CD74

CD74

HLA-DR-gamma; Invariant polypeptide of major histocompatibility complex, class II antigen-associated

 
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-P99731
    Milatuzumab
    		Inhibitor 99.39%
    Milatuzumab (hLL1; MEDI-115) is a humanized anti-CD74 monoclonal antibody. CD74, a integral membrane protein, is associated with the promotion of B-cell growth and survival. Milatuzumab causes free radical oxygen generation, and loss of mitochondrial membrane potential. Milatuzumaba also decreases CD20/CD74 aggregates and cell adhesion, to lead to cell death.
    Milatuzumab
  • HY-N2245
    Schisandrone
    		Inhibitor 99.85%
    Schisandrone, a 4-aryltetralone lignan, is isolated from the dried fruits of Schisandra sphenanthera. Schisandrone is an alpha-hemolysin (Hla) inhibitor that downregulates the transcript levels of hla, agrA and RNAIII. Hla is an integral virulence determinant in Staphylococcus aureus that determines pathogenicity. Schisandrone is a potent inhibitor against MRSA pneumonia.
    Schisandrone
  • HY-P990728
    Bezetabart
    		Inhibitor
    Bezetabart is an anti-CD74 human IgG1 κ monoclonal antibody. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
    Bezetabart
  • HY-N15169
    BG-136
    		Activator
    BG-136 is an innate immune stimulant isolated from Durvillaea Antarctica that can simultaneously stimulate the activation of both innate and adaptive immune cells in the tumor microenvironment (TME), exerting a broad-spectrum antitumor effect.
    BG-136
Cat. No. Product Name / Synonyms Application Reactivity